Comparison of vancomycin-immobilized chiral stationary phase with its derivative for enantioseparation of drugs in high-performance liquid chromatography

Preparation and chromatographic evaluation of a mixed polymer brush–silica stationary phase with temperature-sensitive property

“…High performance liquid chromatography (HPLC) is one of the most commonly used separation methods, and the chromatographic stationary phase is core to promoting the development of HPLC. 1–5 Diversified analytes always need the stationary phase to have different retention mechanisms and a stationary phase where bonding different types of functional molecules can be applied in different separation modes. But very often, classical singe-mode chromatography, e.g.…”

“…High performance liquid chromatography (HPLC) is one of the most commonly used separation methods, and the chromatographic stationary phase is core to promoting the development of HPLC. [1][2][3][4][5] Diversied analytes always need the stationary phase to have different retention mechanisms and a stationary phase where bonding different types of functional molecules can be applied in different separation modes. But very oen, classical singe-mode chromatography, e.g., reversed-phase liquid chromatography (RPLC) for hydrophobic and weak polar compounds, hydrophilic interaction liquid chromatography (HILIC) for highly polar substances, or ion-exchange chromatography (IEC) for charged molecules, are limited in their range of applications.…”