Comparison of Ventricular Ectopic Activity during 24-Hour Monitoring and Exercise Testing in Patients with Coronary Heart Disease

Ryan, Michael; Lown, Bernard; Horn, Howard R.

doi:10.1056/nejm197501302920502

Cited by 225 publications

(36 citation statements)

References 26 publications

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“…[41][42][43] Recent ingestion of alcohol or caffeine may exacerbate arrhythmias. Because exercise increases myocardial oxygen demand, in the presence of CAD, exercise-induced myocardial ischemia could predispose the subject to ectopic activity.…”

Section: Cardiac Arrhythmiasmentioning

confidence: 99%

Exercise Standards for Testing and Training

Fletcher¹,

Balady²,

Amsterdam³

et al. 2001

Circulation

1,681

724

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Section: Cardiac Arrhythmiasmentioning

confidence: 99%

Exercise Standards for Testing and Training

Fletcher¹,

Balady²,

Amsterdam³

et al. 2001

Circulation

1,681

724

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“…Exercise can induce cardiac arrhythmias under several conditions, including diuretic and digitalis therapy. [140][141][142] Recent ingestion of alcohol or caffeine can exacerbate arrhythmias. Because exercise increases myocardial oxygen demand, in the presence of CAD, exercise-induced myocardial ischemia could predispose the subject to ectopic activity.…”

mentioning

confidence: 99%

Exercise Standards for Testing and Training

Fletcher¹,

Ades²,

Kligfield³

et al. 2013

Circulation

1,678

760

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“…All records were analysed by a technician and reviewed by a physician. A modification of the grading system of Ryan et al 5 …”

mentioning

confidence: 99%

Arrhythmia in hypertrophic cardiomyopathy. I: Influence on prognosis.

McKenna¹,

England²,

Doi³

et al. 1981

Heart

397

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SUMMARY In order to examine the association between arrhythmia and subsequent prognosis, 72-hour ambulatory electrocardiographic monitoring was performed in 86 unselected patients with hypertrophic cardiomyopathy. During monitoring 23 patients experienced at least one episode of supraventricular tachycardia and 24 had ventricular tachycardia (of whom 10 had more than three episodes). The patients were then followed for a mean of 2-6 years (range one to four). Seven patients died suddenly. Of these, five had exhibited multiform and paired ventricular extrasystoles and ventricular tachycardia. These arrhythmias were significantly associated with sudden death whereas supraventricular arrhythmias were not. The patients who died suddenly were older and had experienced more symptoms than the survivors, and three had a family history of hypertrophic cardiomyopathy and sudden death. This experience provides the basis for the assessment of treatment in patients with hypertrophic cardiomyopathy and serious ventricular arrhythmia.The high incidence of serious ventricular arrhythmia in hypertrophic cardiomyopathy is now well recognised.' These arrhythmias are often asymptomatic and they are not significantly reduced by betaadrenergic blocking drugs.2 Those who die usually do so suddenly,3 and are often young and asymptomatic.4 The relation ofprevious arrhythmia to sudden death is, however, uncertain. We have assessed the influence of arrhythmia on prognosis in 86 patients with hypertrophic cardiomyopathy who were available for ambulatory electrocardiographic monitoring during 1976 and 1977. Methods

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Comparison of Ventricular Ectopic Activity during 24-Hour Monitoring and Exercise Testing in Patients with Coronary Heart Disease

Cited by 225 publications

References 26 publications

Exercise Standards for Testing and Training

Exercise Standards for Testing and Training

Exercise Standards for Testing and Training

Arrhythmia in hypertrophic cardiomyopathy. I: Influence on prognosis.

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