Comparison of visual and topographic outcomes of deep-anterior lamellar keratoplasty and penetrating keratoplasty in keratoconus

Yüksel, Bora; Kandemir, Baran; Uzunel, Umut Duygu; Çelik, Ozan; Ceylan, Sezgin; Küsbeci, Tuncay

doi:10.18240/ijo.2017.03.10

Cited by 11 publications

(7 citation statements)

References 28 publications

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“…Nevertheless, anterior lamellar keratoplasty still has an advantage over PKP in terms of complications-lower risk of transplant rejection or secondary glaucoma. Further, new techniques using femtosecond laser may improve postoperative visual acuity in those patients [26][27][28][29]. Decrease in percentage of DALK was observed in our study, although keratoconus remained a second most frequent indication through all analyzed years.…”

Section: Plos Onesupporting

confidence: 54%

Indications and techniques of corneal transplants performed in one center in Southern Poland, in the years 2001–2020

et al. 2022

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Purpose The study aimed to evaluate changes over a period of time in techniques and indications for corneal transplantation in a single center in Poland. Methods Retrospective analysis of corneal transplants performed at the Ophthalmology Department of the District Railway Hospital in Katowice in 2001–2020. Data on indications and surgical technique were collected. Results A total of 3021 corneal transplantations were performed in the years 2000–2020. The most common technique was penetrating keratoplasty (69,54%), then lamellar grafts—both anterior and posterior (19,63%), and limbal grafts (10,82%). Only in 2007 the number of lamellar keratoplasties exceeded the number of penetrating grafts and accounted for 108 (54,55%), including 85 (42,93%) of Descemet Stripping Automated Endothelial Keratoplasty. The only noticeable trend in changing techniques was a decrease in the number of performed deep anterior lamellar keratoplasties (r 2 = -0.21) over the last seven years. Main indications included bullous keratopathy (23,22%), following keratoconus (18,59%), leukoma (14,67%), keratitis and perforation (14,3%), Fuchs dystrophy (11,4%), and regrafts (7,22%). Leukoma and bullous keratopathy as an indications for corneal transplant have been declining over the years (r2 = 0.60 and r2 = 0.30 respectively). Consecutively, indications such as fuchs dystrophy, regraft and keratitis perforation have increased (r2 = 0.05, r2 = 0.50, r2 = 0.33) Conclusions The number of keratoplasties gradually increased from 2001 to 2020. It could be possible that the development and spread of new therapeutic alternatives, like corneal cross-linking and scleral lenses, have contributed to the decrease in deep anterior lamellar keratoplasty performed. There was an increasing trend in the percentage of penetrating keratoplasties for failed grafts, Fuchs dystrophy and infectious keratitis.

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Section: Plos Onesupporting

confidence: 54%

Indications and techniques of corneal transplants performed in one center in Southern Poland, in the years 2001–2020

et al. 2022

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“…During DALK, the endothelium and Descemet membrane are separated from the corneal stroma through intrastromal air injection (big-bubble technique). 31 Yüksel et al 32 reported that big-bubble DALK results in earlier visual improvement than does PKP. However, at 1 year, the visual and topographic results are similar to those of PKP.…”

Section: Discussionmentioning

confidence: 99%

Trends in Research Related to Keratoconus From 2009 to 2018: A Bibliometric and Knowledge Mapping Analysis

Zhao

Zhang

et al. 2019

Cornea

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“…The reported rates of postoperative complications such as graft rejection, secondary glaucoma, complicated cataracts, and constant endothelial cell loss are higher with PK. 135 , 161 , 162 , 163 , 164 , 165 , 166 …”

Section: Methodsmentioning

confidence: 99%

Updates on Managements for Keratoconus

Mohammadpour

Heidari

Hashemi

2018

Journal of Current Ophthalmology

101

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PurposeKeratoconus is a progressive disease of the cornea which can lead to blindness as irregular astigmatism increases. Currently, a variety of methods are available for the treatment of keratoconus, and in certain cases, it may be difficult to choose the most appropriate option. This article reviews available treatment modalities for keratoconus to provide the practitioner with practical and useful information for selecting the most suitable option for each individual patient.MethodsTo review treatment methods for different stages of keratoconus, PubMed (United States National Library of Medicine) and Scopus (Elsevier BV) databases were searched using the keywords “keratoconus”, “contact lens”, “cross-linking”, “Intacs”, “keratoplasty”, “gene therapy”, and “irregular astigmatism”, and related articles were reviewed based on disease assessment parameters and treatment methods.ResultsVarious methods are available for the treatment of keratoconus: eyeglasses and contact lenses in the early stages, cross-linking for stabilizing disease progression, intrastromal corneal ring segments (ICRS) for reducing refractive errors or flattening the cornea, and penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK), conductive keratoplasty, gene therapy and more recently, bowman layer transplantation (BL transplantation) in advanced stages of the disease. To achieve optimum results, it is essential to choose the best option for each individual patient.ConclusionsA commonality of the reviewed papers was the advancement of novel diagnostic and treatment methods in ophthalmology, which can delay the need for corneal grafting. A better understanding of keratoconus treatment options can help enhance visual rehabilitation and prevent blindness in keratoconus patients.

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Comparison of visual and topographic outcomes of deep-anterior lamellar keratoplasty and penetrating keratoplasty in keratoconus

Cited by 11 publications

References 28 publications

Indications and techniques of corneal transplants performed in one center in Southern Poland, in the years 2001–2020

Indications and techniques of corneal transplants performed in one center in Southern Poland, in the years 2001–2020

Trends in Research Related to Keratoconus From 2009 to 2018: A Bibliometric and Knowledge Mapping Analysis

Updates on Managements for Keratoconus

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