Comparison of Zinc,Vitamin A &amp;D Serum Levels Between Children With Respiratory Tract Infection And Healthy Individuals in two Iranian Referral Hospitals

Shokrollahi, Mohammad Reza; Movahedi, Zahra; Nia, Shima Javadi; Asl, H Masoumi; Heydari, Hassan; Tabatabaei, Azardokht

doi:10.9790/0853-1509126469

Cited by 1 publication

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“…The studies currently available in the literature are burdened by a lack of reproducibility, methodological imprecision, low population size and the heterogeneity of the population studied and of the results obtained, so it is not possible to recommend the use of trace elements in the prevention of RRIs. In response to the outcome about the possible relationship between reduced serum levels of vitamin D/ vitamin A/ vitamin E and increased risk of RRIs in children, 7 observational studies of very low methodological quality and with very heterogeneous results were included [ 53 – 56 , 58 , 59 , 69 ]. The outcomes are different: 3 studies [ 54 , 56 , 59 ] enrolled subjects with RRIs, 1 study [ 55 ] selected subjects with AOM, 1 study [ 53 ] with recurrent tonsillitis, and, lastly, Shokrollahi’s study assessed subjects with lower respiratory tract infections.…”

Section: Resultsmentioning

confidence: 99%

Prevention of recurrent respiratory infections

et al. 2021

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Recurrent respiratory infections (RRIs) are a common clinical condition in children, in fact about 25% of children under 1 year and 6% of children during the first 6 years of life have RRIs. In most cases, infections occur with mild clinical manifestations and the frequency of episodes tends to decrease over time with a complete resolution by 12 years of age. However, RRIs significantly reduce child and family quality of life and lead to significant medical and social costs.Despite the importance of this condition, there is currently no agreed definition of the term RRIs in the literature, especially concerning the frequency and type of infectious episodes to be considered. The aim of this consensus document is to propose an updated definition and provide recommendations with the intent of guiding the physician in the complex process of diagnosis, management and prevention of RRIs.

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