1989
DOI: 10.1007/bf01701925
|View full text |Cite
|
Sign up to set email alerts
|

Comparison study of the sensitivities of some indices of DDT exposure in human blood and urine

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

1
1
0

Year Published

1990
1990
2020
2020

Publication Types

Select...
6

Relationship

0
6

Authors

Journals

citations
Cited by 8 publications
(2 citation statements)
references
References 18 publications
1
1
0
Order By: Relevance
“…The preferential increase of 6b-hydroxylase activity by DDT observed in this study suggests an inductive effect on hepatic CYP3A, despite that a significant induction was not observed in male rats (Sierra-Santoyo et al 2000). The increase in 6b-hydroxylase activity is in agreement with the increased cortisol catabolism observed in DDTexposed humans excreting significant amounts of 6b-hydroxycortisol in urine (Poland et al 1970;Nhachi and Loewenson 1989).…”
Section: Discussionsupporting
confidence: 87%
“…The preferential increase of 6b-hydroxylase activity by DDT observed in this study suggests an inductive effect on hepatic CYP3A, despite that a significant induction was not observed in male rats (Sierra-Santoyo et al 2000). The increase in 6b-hydroxylase activity is in agreement with the increased cortisol catabolism observed in DDTexposed humans excreting significant amounts of 6b-hydroxycortisol in urine (Poland et al 1970;Nhachi and Loewenson 1989).…”
Section: Discussionsupporting
confidence: 87%
“…Therefore, it is probable that levels of other endobiotics metabolized by this enzyme are also modified. Moreover, it was shown in humans that exposure to DDT increased estradiol metabolism (Poland et al, 1970;Nhachi and Loewenson, 1989). This is of particular interest because estradiol metabolites, such as 16-hydroxyestradiol, are ER agonists associated with increased breast cancer incidence (Kabat et al, 1997).…”
mentioning
confidence: 99%