Comparison study on the effect of gold nanoparticles shape in the forms of star, hallow, cage, rods, and Si-Au and Fe-Au core-shell on photothermal cancer treatment

Pakravan, Asrin; Salehi, Roya; Mahkam, Mehrdad

doi:10.1016/j.pdpdt.2020.102144

Cited by 37 publications

(20 citation statements)

References 71 publications

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“…When Au is coupled with MMSN, the photothermal effect increased to a certain extent, which may be attributed to Au's surface electron oscillation after absorbing near-infrared light. As Fe 3 O 4 microspheres had stronger absorption in the near-infrared region than Au, and MNP had better photothermal conversion under nearinfrared light, 32,33 MNP temperature heating rate was higher than MMSN-Au under PT. However, things were different for magnetothermal properties because Au nanoparticles could not generate heat in an alternating electric field.…”

Section: Magnetothermal and Photothermal Propertiesmentioning

confidence: 99%

Au Catalyzing Control Release NO in vivo and Tumor Growth-Inhibiting Effect in Chemo-Photothermal Combination Therapy

Zhang

Zhou

et al. 2021

IJN

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Introduction:Aim to obtain a NO donor that can control released NO in vivo with the high efficacy of tumor suppression and targeting, a nanoplatform consisting of FA-Fe 3 O 4 @mSiO 2 -Au/DOX was constructed. Methods: In vitro, the nanoplatform catalyzed NO's release with the maximum value of 4.91 μM within 60 min at 43°C pH=5.0, which was increased by 1.14 times when the temperature was 37°C. In vivo, 11.7 μg Au in the tumor tissue was found to catalyze S-nitrosoglutathione continuously, and 54 μM NO was checked out in the urine. Results and Discussion: The high concentration of NO was found to increase the apoptotic rate and to reduce tumor proliferation. In the chemo-photothermal combination therapy, the tumor inhibition rate was increased up to 94.3%, and Au's contribution from catalyzing NO release NO was 8.17%.

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Section: Magnetothermal and Photothermal Propertiesmentioning

confidence: 99%

Au Catalyzing Control Release NO in vivo and Tumor Growth-Inhibiting Effect in Chemo-Photothermal Combination Therapy

Zhang

Zhou

et al. 2021

IJN

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“…Overall, the aspect ratio or length-to-diameter ratio on the shape of Au nanoparticles will be proportional to the release rate of liposomes. As an example of common shapes, this effectiveness is roughly in the order of hollow irregular geometry > rod > cube > sphere. − …”

Section: Photoresponsive Liposomes Based On Au Nanoparticlesmentioning

confidence: 99%

Recent Development of Photoresponsive Liposomes Based on Organic Photosensitizers, Au Nanoparticles, and Azobenzene Derivatives for Nanomedicine

Pan

et al. 2022

ACS Appl. Nano Mater.

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Photoresponsive liposomes are controlled-release liposomes modified by photoresponsive materials. They use light with high spatial and temporal precision as a means of regulation. After excitation by light at appropriate wavelengths, photoresponsive liposomes can influence the permeability of phospholipid bilayers through the photothermal or photoisomerization effect of photoresponsive materials. The photothermal effect causes the phospholipid layer to become dispersed by local heating, and the photoisomerization effect modulates the release behavior by establishing permeation channels on the phospholipid layer through changes in the dipole moments of azobenzene derivatives. Currently, photoresponsive liposomes are widely used as a cutting-edge strategy for nanomedicine. In this paper, three types of photoresponsive liposomes based on organic photosensitizers, Au nanoparticles, and azobenzene derivatives with abundant research reports were introduced based on the differences in the photoresponse principles and forms of different photoresponsive materials. This review aims to reflect the differences in the structures, properties, photoresponsive materials, and principles of action of different photoresponsive liposomes. Moreover, this work outlines the current status of their application in the field of nanomedicine.

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“…With the rapid advances in nanotechnology, there are a variety of synthetic methods available to researchers to obtain gold nanoparticles with suitable structures and features for PDT applications [ 143 ]. In addition to the various physicochemical properties, the additional chemical modification potential mentioned above could improve bioavailability and usability, suggesting gold nanoparticles as a promising candidate for clinical cancer treatment.…”

Section: Nanotechnology For Enhanced Photodynamic Therapymentioning

confidence: 99%

Nanomedicine in Clinical Photodynamic Therapy for the Treatment of Brain Tumors

Kim

Lee

2022

Biomedicines

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The current treatment for malignant brain tumors includes surgical resection, radiotherapy, and chemotherapy. Nevertheless, the survival rate for patients with glioblastoma multiforme (GBM) with a high grade of malignancy is less than one year. From a clinical point of view, effective treatment of GBM is limited by several challenges. First, the anatomical complexity of the brain influences the extent of resection because a fine balance must be struck between maximal removal of malignant tissue and minimal surgical risk. Second, the central nervous system has a distinct microenvironment that is protected by the blood–brain barrier, restricting systemically delivered drugs from accessing the brain. Additionally, GBM is characterized by high intra-tumor and inter-tumor heterogeneity at cellular and histological levels. This peculiarity of GBM-constituent tissues induces different responses to therapeutic agents, leading to failure of targeted therapies. Unlike surgical resection and radiotherapy, photodynamic therapy (PDT) can treat micro-invasive areas while protecting sensitive brain regions. PDT involves photoactivation of photosensitizers (PSs) that are selectively incorporated into tumor cells. Photo-irradiation activates the PS by transfer of energy, resulting in production of reactive oxygen species to induce cell death. Clinical outcomes of PDT-treated GBM can be advanced in terms of nanomedicine. This review discusses clinical PDT applications of nanomedicine for the treatment of GBM.

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Comparison study on the effect of gold nanoparticles shape in the forms of star, hallow, cage, rods, and Si-Au and Fe-Au core-shell on photothermal cancer treatment

Cited by 37 publications

References 71 publications

Au Catalyzing Control Release NO in vivo and Tumor Growth-Inhibiting Effect in Chemo-Photothermal Combination Therapy

Au Catalyzing Control Release NO in vivo and Tumor Growth-Inhibiting Effect in Chemo-Photothermal Combination Therapy

Recent Development of Photoresponsive Liposomes Based on Organic Photosensitizers, Au Nanoparticles, and Azobenzene Derivatives for Nanomedicine

Nanomedicine in Clinical Photodynamic Therapy for the Treatment of Brain Tumors

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