2015
DOI: 10.13005/bpj/772
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Comparison the Efficacy of Intratympanic Injections of Methylprednisolone and Gentamicin to Control Vertigo in Unilateral Meniere’s Disease

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Cited by 8 publications
(4 citation statements)
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“…Steroid therapy via IT delivery appears to have less risk of treatment-associated hearing loss than IT gentamicin therapy, 0% to 8% versus 12.5% to 15.4%, respectively. 279,280,282,284 One study found a similar improvement in aural fullness with both IT steroid (38%) and IT gentamicin therapy (31%). 280 As in sudden hearing loss, 99 2 SRs suggest that IT steroid therapy may have a role in salvaging hearing secondary to a MD flare, 285,286 although 1 RCT found no benefit regarding hearing salvage.…”
Section: Supporting Textmentioning
confidence: 93%
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“…Steroid therapy via IT delivery appears to have less risk of treatment-associated hearing loss than IT gentamicin therapy, 0% to 8% versus 12.5% to 15.4%, respectively. 279,280,282,284 One study found a similar improvement in aural fullness with both IT steroid (38%) and IT gentamicin therapy (31%). 280 As in sudden hearing loss, 99 2 SRs suggest that IT steroid therapy may have a role in salvaging hearing secondary to a MD flare, 285,286 although 1 RCT found no benefit regarding hearing salvage.…”
Section: Supporting Textmentioning
confidence: 93%
“…297 Steroid therapy via IT delivery may be considered an alternative for oral steroid therapy 258,288,298,299 and IT gentamicin therapy. [279][280][281][282] Oral steroids have significant risk of side effects, 99,298 and patients with usable hearing-class A or B as defined by AAO-HNSF guidelines for the evaluation of hearing preservation in acoustic neuroma (vestibular schwannoma) 300 -may be hesitant to undergo an ablative inner ear therapy with a known potential for hearing loss. As such, there is a significant role for patient preference when offering IT steroid therapy.…”
Section: Supporting Textmentioning
confidence: 99%
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