Comparison Trial between I-SCAN-Optical Enhancement and Chromoendoscopy for Evaluating the Horizontal Margins of Gastric Epithelial Neoplasms

Koh, Myeongseok; Lee, Jong Yoon; Han, Song Hee; Jeon, Seong Woo; Kim, Su Jin; Cho, Joo Young; Kim, Seong Hwan; Jang, Jun‐Bock; Baik, Gwang Ho; Jang, Jin Seok

doi:10.5009/gnl220025

Cited by 4 publications

(3 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The I-SCAN method, developed by PENTAX (Tokyo, Japan), consists of various types of post-processing images to enhance the surface, contrast, and tone. In a comparison trial, i-SCAN showed similar results compared with dye CE (acetic acid and indigo carmine) to delineate the margins of gastric lesions [51].…”

Section: Virtual Chromoendoscopymentioning

confidence: 90%

Endoscopic Imaging for the Diagnosis of Neoplastic and Pre-Neoplastic Conditions of the Stomach

Martins

Moura

Kum

et al. 2023

Cancers

View full text Add to dashboard Cite

Gastric cancer is an aggressive disease with low long-term survival rates. An early diagnosis is essential to offer a better prognosis and curative treatment. Upper gastrointestinal endoscopy is the main tool for the screening and diagnosis of patients with gastric pre-neoplastic conditions and early lesions. Image-enhanced techniques such as conventional chromoendoscopy, virtual chromoendoscopy, magnifying imaging, and artificial intelligence improve the diagnosis and the characterization of early neoplastic lesions. In this review, we provide a summary of the currently available recommendations for the screening, surveillance, and diagnosis of gastric cancer, focusing on novel endoscopy imaging technologies.

show abstract

Section: Virtual Chromoendoscopymentioning

confidence: 90%

Endoscopic Imaging for the Diagnosis of Neoplastic and Pre-Neoplastic Conditions of the Stomach

Martins

Moura

Kum

et al. 2023

Cancers

View full text Add to dashboard Cite

show abstract

“…Several studies have found that i-Scan does not provide significant advantages in detecting gastric cancer lesions or determining their extent when compared with high-definition white light endoscopy or pigmented endoscopy. However, the use of i-Scan could largely reduce the need for unnecessary biopsies compared to WLE (with a mean number of biopsies per patient of 3.27 and 7.3, respectively) 79 , 80 .…”

Section: Endoscopy Screening For Early Gastric Cancermentioning

confidence: 99%

Global progress and future prospects of early gastric cancer screening

Huang,

Shao,

et al. 2024

J. Cancer

View full text Add to dashboard Cite

Gastric cancer is a prevalent malignancy that poses a serious threat to global health. Despite advances in medical technologies, screening methods, and public awareness, gastric cancer remains a significant cause of morbidity and mortality worldwide. Early gastric cancer frequently does not present with characteristic symptoms, while advanced stage disease is characterized by a dismal prognosis. As such, early screening in gastric cancer is of great importance. In recent years, advances have been made globally in both clinical and basic research for the screening of early gastric cancer. The current predominant screening methods for early gastric cancer include imaging screening, endoscopic screening and serum biomarker screening. Imaging screening encompasses upper gastrointestinal barium meal, multidimensional spiral computed tomography (MDCT), Magnetic resonance imaging (MRI), and ultrasonography. Endoscopic screening methods include white light endoscopy, chromoendoscopy, computed virtual chromoendoscopy, and other endoscopic techniques like endocytoscopy, confocal laser endomicroscopy, optical coherence tomography and so on. Biomarkers screening involves the assessment of conventional biomarkers such as CEA, CA19-9 and CA72-4 as well as more emerging biomarkers such as peptides (PG, G-17, GCAA, TAAs and others), DNA (cfDNA, DNA methylation, MSI), noncoding RNA (miRNA, lncRNA, circRNA, and tsRNA) and others. Each screening method has its strengths and limitations. This article systematically summarizes worldwide progress and future development of early gastric cancer screening methods to provide new perspectives and approaches for early diagnostic and treatment advancements in gastric cancer worldwide.

show abstract

“…This is accomplished by linking the highest points of the hemoglobin absorption spectrum (at 415, 540, and 570 nm), resulting in the creation of a seamless spectrum of wavelengths, which is almost identical to the principle of NBI [ 24 ]. Although i-scan OE operates on a similar principle as NBI, a few studies have suggested new diagnostic criteria, which are different from those of NBI [ 25 , 26 , 27 , 28 ]. However, they are not commonly used by many endoscopists.…”

Section: Introductionmentioning

confidence: 99%

The Utility of Narrow-Band Imaging International Colorectal Endoscopic Classification in Predicting the Histologies of Diminutive Colorectal Polyps Using I-Scan Optical Enhancement: A Prospective Study

Kang,

Lee,

Lee

2023

Diagnostics

Self Cite

View full text Add to dashboard Cite

(1) Background: This study aimed to evaluate the accuracy of predicting the histology of diminutive colonic polyps (DCPs) (≤5 mm) using i-scan optical enhancement (OE) based on the narrow-band imaging international colorectal endoscopic (NICE) classification. The study compared the diagnostic accuracy between experts who were already familiar with the NICE classification and trainees who were not, both before and after receiving brief training on the NICE classification. (2) Method: This prospective, single-center clinical trial was conducted at the Dong-A University Hospital from March 2020 to August 2020 and involved two groups of participants. The first group comprised two experienced endoscopists who were proficient in using i-scan OE and had received formal training in optical diagnosis and dye-less chromoendoscopy (DLC) techniques. The second group consisted of three endoscopists in the process of training in internal medicine at the Dong-A University Hospital. Each endoscopist examined the polyps and evaluated them using the NICE classification through i-scan OE. The results were not among the participants. Trained endoscopists were divided into pre- and post-training groups. (3) Results: During the study, a total of 259 DCPs were assessed using i-scan OE by the two expert endoscopists. They made real-time histological predictions according to the NICE classification criteria. For the trainee group, before training, the area under the receiver operating characteristic curves (AUROCs) for predicting histopathological results using i-scan OE were 0.791, 0.775, and 0.818. However, after receiving training, the AUROCs improved to 0.935, 0.949, and 0.963, which were not significantly different from the results achieved by the expert endoscopists. (4) Conclusions: This study highlights the potential of i-scan OE, along with the NICE classification, in predicting the histopathological results of DCPs during colonoscopy. In addition, this study suggests that even an endoscopist without experience in DLC can effectively use i-scan OE to improve diagnostic performance with only brief training.

show abstract

Comparison Trial between I-SCAN-Optical Enhancement and Chromoendoscopy for Evaluating the Horizontal Margins of Gastric Epithelial Neoplasms

Cited by 4 publications

References 22 publications

Endoscopic Imaging for the Diagnosis of Neoplastic and Pre-Neoplastic Conditions of the Stomach

Endoscopic Imaging for the Diagnosis of Neoplastic and Pre-Neoplastic Conditions of the Stomach

Global progress and future prospects of early gastric cancer screening

The Utility of Narrow-Band Imaging International Colorectal Endoscopic Classification in Predicting the Histologies of Diminutive Colorectal Polyps Using I-Scan Optical Enhancement: A Prospective Study

Contact Info

Product

Resources

About