Comparisons of results between three in-house biochemistry analyzers and a commercial laboratory analyzer for feline plasma using multiple quality specifications

Baral, Randolph M.; Dhand, Navneet K.; Krockenberger, M. B.; Govendir, Merran

doi:10.1007/s00580-014-2035-2

Cited by 3 publications

(3 citation statements)

References 31 publications

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“…Using ASVCP recommended TE a acceptability limits to evaluate clinical rather than analytic acceptability in a method comparison dataset have been used in at least 2 studies, with the authors considering either > 90% or > 95% of measurements within these limits as acceptable . More than 95% of results fell within the TE a coverage range for albumin, creatinine, glucose, phosphorus, total proteins, and urea when comparing feline plasma on the VetTest and Cobas (AST, CK, and GGT not investigated) .…”

Section: Discussionmentioning

confidence: 99%

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Method comparison and generation of plasma biochemistry RIs for the White rhinoceros on a point‐of‐care and wet chemistry analyzer

Hooijberg

Steenkamp

Buss

et al. 2017

Veterinary Clinical Pathol

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Section: Discussionmentioning

confidence: 99%

“…The clinical relevance of method differences was assessed: a TE a range was calculated for each Cobas measurement and it was determined whether the matching VetTest result was within this range . Methods were considered clinically equivalent if > 95% of VetTest results fell into this range, for each analyte …”

Section: Methodsmentioning

confidence: 99%

Method comparison and generation of plasma biochemistry RIs for the White rhinoceros on a point‐of‐care and wet chemistry analyzer

Hooijberg

Steenkamp

Buss

et al. 2017

Veterinary Clinical Pathol

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“…2012, Baral et al . 2015b). Of the electrolytes measured, [Na + ] and [K + ] were more prone to error.…”

Section: Introductionmentioning

confidence: 99%

Electrolyte measurements differ between point‐of‐care and reference analysers in dogs with hypoadrenocorticism

Fowlie

Spence

Roberts

et al. 2020

J of Small Animal Practice

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Dogs treated for hypoadrenocorticism are monitored through analysis of their blood electrolytes. This is routinely performed with point-of-care analysers and doses of medications are adjusted based on the results. objectIves: To investigate the performance of two point-of-care analysers (IDEXX Catalyst Dx and IDEXX VetStat) against a reference laboratory method for the measurement of blood sodium, potassium and chloride concentrations, as well as sodium: potassium ratios, in dogs diagnosed with and treated for hypoadrenocorticism. Methods: Forty-eight dogs were enrolled into a prospective cross-sectional study. Paired blood samples were taken and tested on two point-of-care analysers and at a reference laboratory. Statistical analysis was then performed with Bland-Altman analysis and Passing-Bablok regression. The clinical effects of inaccurate electrolyte analysis were investigated. results: In total, 329 samples were tested on the Catalyst analyser, while another 72 samples were tested on the VetStat. Passing-Bablok regression identified both proportional and constant bias for some analytes. There was poor agreement between sodium and chloride concentrations on both analysers. Both analysers tended to give higher results than the reference method for all analytes, except for potassium when measured on the VetStat. clInIcal sIgnIfIcance: There are inherent differences between the electrolyte concentrations measured by these two point-of-care analysers and reference laboratory methods in dogs with hypoadrenocorticism.

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Clinical Pathology

Baral,

Freeman

2025

The Cat

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Comparisons of results between three in-house biochemistry analyzers and a commercial laboratory analyzer for feline plasma using multiple quality specifications

Abstract: Comparisons of results between three in-house biochemistry analyzers and a commercial laboratory analyzer for feline plasma using multiple quality specifications. Comparative Clinical Pathology, 24(5), 1075-1089.

Cited by 3 publications

References 31 publications

Method comparison and generation of plasma biochemistry RIs for the White rhinoceros on a point‐of‐care and wet chemistry analyzer

Method comparison and generation of plasma biochemistry RIs for the White rhinoceros on a point‐of‐care and wet chemistry analyzer

Electrolyte measurements differ between point‐of‐care and reference analysers in dogs with hypoadrenocorticism

Clinical Pathology

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