Compatibilities and Incompatibilities of Some Parenteral Medication

Bogash, Robert C.

doi:10.1093/ajhp/12.4.445

Cited by 4 publications

(4 citation statements)

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“…To our knowledge, the first manuscript on compatibilities and incompatibilities was published in 1955 [11]. Another two publications followed in 1961 [12,13].…”

Section: Discussionmentioning

confidence: 99%

European Databases on Stability and Compatibility of Injectable Medicinal Products in Europe

Hecq

Krämer

Vigneron

2020

Pharmaceutical Technology in Hospital Pharmacy

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AbstractIn hospitals, the majority of medication therapy is administered intravenously. Especially, in intensive care units, simultaneous of various injectable drugs is a common practice Drug incompatibilities have been reported to be associated with up to 60 % of all serious and life-threatening adverse drug events. Several databases are used by hospital pharmacists to answer the questions of (in)compatibility of co-administered injectable drugs. The objective of this article is to present the European databases on compatibility and stability of injectable drugs. According to a questionnaire which was sent to the National Hospital Pharmacy Associations of the 28 countries of European Community there are three national databases available in EU countries which are in alphabetical order, Belgium, France and Germany. The Belgian database is dedicated to injectable medications, is updated and distributed annually in French language on a USB key. STABILIS® is an international database giving information with pictograms translated into 29 languages. This database contains also monographs of non-injectable drugs. The internet-based ADKA STABIL-Datenbank is focused on anticancer drug therapy, listing detailed datasets in German language on stability and compatibility including the references.

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“…To our knowledge, the first manuscript on compatibilities and incompatibilities was published in 1955 [11]. Another two publications followed in 1961 [12,13].…”

Section: Discussionmentioning

confidence: 99%

European Databases on Stability and Compatibility of Injectable Medicinal Products in Europe

Hecq

Krämer

Vigneron

2020

Pharmaceutical Technology in Hospital Pharmacy

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“…additives increased substantially. Pharmacists also had long expressed concerns about incompatibilities in the use of injections 38 ; they reiterated those concerns in 1966. 39 Drug additives were present in 70% of one hospital's LVISs administered in 1966 and in 86% in another hospital in 1968.…”

Section: Milestones In the Technology Of IV Therapymentioning

confidence: 99%

History of sterile compounding in U.S. hospitals: Learning from the tragic lessons of the past

Myers

2013

American Journal of Health-System Pharmacy

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Over the years, there have been numerous exhortations for voluntary better performance in sterile compounding. In addition, professional leadership has been vigorous and extensive in the form of guidance, publications, education, enforceable standards, and development of various associations and organizations dealing with safe compounding practices. Yet problems continue to occur. We must engage in diligent learning from the injuries and tragedies that have occurred. Assuming that we are already doing all we can to avoid problems would be an abdication of the professional mission of pharmacists. It would be wrong thinking to assume that the recent problems in large-scale compounding pharmacies are the only problems that warrant attention. It is time for a systematic assessment of the nature and the dimensions of the problems in every type of setting where sterile compounding occurs. It also is time for some innovative thinking about ensuring safety in sterile compounding.

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“…10 products at the time of preparation and four hours later. If no particulate matter appeared, then the LVP products were rated "compatible."…”

Section: Literature Reviewmentioning

confidence: 99%

“…This information will be used by Abbott Laboratories in developing study projects on incompatibilities. 10. The American Society of Hospital Pharmacists should consider establishment of laboratory facilities to conduct and coordinate studies on incompatibilities of LVP vehicles and products.…”

Section: Literature Reviewmentioning

confidence: 99%

Incompatibilities in Large Volume Parenterals

Hd¹

1977

Drug Intelligence & Clinical Pharmacy

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Compatibilities and Incompatibilities of Some Parenteral Medication

Cited by 4 publications

References 0 publications

European Databases on Stability and Compatibility of Injectable Medicinal Products in Europe

European Databases on Stability and Compatibility of Injectable Medicinal Products in Europe

History of sterile compounding in U.S. hospitals: Learning from the tragic lessons of the past

Incompatibilities in Large Volume Parenterals

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