Most of the studies about control, automation, optimization and supervision of building HVAC systems are about the steady-state regime, i.e. when the equipment is already working on their setpoints. In this work, it is defined an approach for multi-HVAC systems to reach the setpoint at the startup, so that other steady statebased strategies can smoothly come into operation to control and supervise their operations. The proposed approach for the management of the transient regime for multi-HVAC systems is based on the "Autonomic Cycle of Data Analysis Tasks" concept. In this case, it is composed of two data analysis tasks: one for determining if the system is going towards the defined operational setpoint, and if it was not the case, another for reconfiguring the operational mode of the multi-HVAC system to redirect it. The proposal is proved in a real context that characterizes one multi-HVAC system and its operational setpoints. The performance obtained from the experiments in diverse situations is encouraging, since they show how this approach leads the multi-HVAC system to reach the setpoint optimizing contradictory objectives, such as to attain the desired comfort, or reduce the energy costs, among others.