Competition between student groups in the protein production challenge

Lefebvre, Brian G.; Connell, Loren; Dahm, Kevin

doi:10.1016/j.ece.2008.11.001

Cited by 7 publications

(3 citation statements)

References 12 publications

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“…To date, three modules have been developed: 1. anion exchange chromatography with DsRed2 and EGFP 11 2. anion exchange chromatography with EGFP and C. anabaena flavodoxin 12 3. protein production project with DsRed2, EGFP, and flavodoxin 13 Separation of DsRed2 and EGFP by anion exchange is challenging, making this experiment sensitive to experimental conditions and suitable for extended experimentation. This anion exchange chromatography experiment is appropriate as a full-scale laboratory for unit operations laboratory courses and upper-level electives on biochemical engineering or bioseparations.…”

Section: Resultsmentioning

confidence: 99%

Illustrating Bioseparations Using Colorful Proteins

Lefebvre¹,

Farrell²,

Slater³

2008 Annual Conference &Amp; Exposition Proceedings

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The field of chemical engineering is undergoing a rapid change. Advances in biology are prompting new discoveries in the biotechnology, pharmaceutical, medical technology, and chemical industries. Developing commercial-scale processes based on these advances requires that new chemical engineers clearly understand the biochemical principles behind the technology, in addition to developing a firm grasp of chemical engineering principles. 1 To ensure that chemical engineering students are prepared to contribute to these expanding industries, this project will incorporate hands-on and visually appealing experiments using colorful proteins to teach biochemical engineering and bioseparation principles.The project consists of eight modules that introduce students to multidisciplinary engineering principles through the production and purification of colorful proteins. The project adapts experiments from the biochemistry and molecular biology education literature by expanding the scope from one colorful protein to many. Four colorful proteins with different physical properties will be mixed and separated using a variety of chromatography and membrane separations, which will illustrate the basis of bioprocess design. To maximize student interest and learning, this material will be implemented in a hands-on and visually appealing format exemplifying the "hands-on / minds-on" approach to engineering education. The engineering goals of this project are:• to explore bioseparation techniques • to expose students to bioprocess design principles • to study the performance of bioseparation processes using engineering principles • to evaluate factors influencing the performance of bioseparation processes To date, work has focused on two chromatographic separation techniques. Learning modules on these two techniques will be presented.

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Section: Resultsmentioning

confidence: 99%

Illustrating Bioseparations Using Colorful Proteins

Lefebvre¹,

Farrell²,

Slater³

2008 Annual Conference &Amp; Exposition Proceedings

View full text Add to dashboard Cite

show abstract

“…Three examples 14,15,16 of refereed journal articles that used assessment data collected with the instruments described in this paper are described briefly:…”

Section: Publication Of Pedagogical Scholarshipmentioning

confidence: 99%

“…The results showed superior performance for the students who completed the protein production challenge. 16…”

Section: Publication Of Pedagogical Scholarshipmentioning

confidence: 99%

Practical, Efficient Strategies For Assessment Of Engineering Projects And Engineering Programs

Dahm¹

2010 Annual Conference &Amp; Exposition Proceedings

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The process of seeking and gaining accreditation for an engineering program was substantially changed ten years ago when the EC2000 criteria were implemented. (The moniker EC2000 is no longer in use; they are now simply the ABET criteria.) Programs must now define goals and objectives for their program, provide evidence that graduates are meeting these objectives, and demonstrate evidence of continuous improvement. These accreditation criteria present programs with significant challenges. Departments must determine what data are needed and collect it regularly. To be sustainable, assessment plans must make efficient use of faculty time. This paper will present strategies for collecting assessment data that serves multiple purposes beyond accreditation, using the Rowan University Junior/Senior Engineering Clinic as an example.

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Two challenge-based laboratories for introducing undergraduate students to biomaterials

Vernengo

Dahm

2012

Education for Chemical Engineers

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Competition between student groups in the protein production challenge

Cited by 7 publications

References 12 publications

Illustrating Bioseparations Using Colorful Proteins

Illustrating Bioseparations Using Colorful Proteins

Practical, Efficient Strategies For Assessment Of Engineering Projects And Engineering Programs

Two challenge-based laboratories for introducing undergraduate students to biomaterials

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