Complaints of sore throat after tracheal intubation

Bíró, Péter; Seifert, Burkhardt; Pasch, Th.

doi:10.1017/s0265021505000529

Cited by 215 publications

(245 citation statements)

References 21 publications

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“…22,23 In our study, two study groups were not statistically different in terms of gender, age, weight, duration of surgery and duration of intubation.…”

Section: Discussionmentioning

confidence: 46%

Efficacy of Ketamine Gargle in Attenuating Postoperative Sore Throat

Sharma¹,

Vaidya

Chand

2015

J Lumbini Med Coll

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ABSTRACT:Introduction: Postoperative sore throat (POST) is a common complication of general anesthesia with endotracheal intubation that affects the patient satisfaction after surgery. The aim of the study was to compare the effectiveness of ketamine gargle with placebo in preventing POST after endotracheal intubation. Methods: Sixty eight patients scheduled for elective surgery under general anesthesia were enrolled in this study. Patients were randomly allocated into two groups, 33 in study group and 35 in control group. Study group patients were asked to gargle with ketamine (50 mg in 1 ml mixed with 29 ml of drinking water) 10 minutes before induction for 30 seconds. Controls were made to do so with 30 ml of drinking water. POST was graded at one, two, four, and 24 hrs after operation on a four-point scale (0-3). The outcome measures were compared between two groups in terms of occurrence of POST and severity of POST at one, two, four, and 24 hr to determine the efficacy of ketamine. Results: Occurrence of POST was significantly less in study group at four hours. Severity of POST was significantly low in study group at one, two and four hours as compared to that in controls. It was comparable at 24 hours. Conclusion: Ketamine gargle significantly reduced the occurrence and severity of POST.

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“…22,23 In our study, two study groups were not statistically different in terms of gender, age, weight, duration of surgery and duration of intubation.…”

Section: Discussionmentioning

confidence: 46%

Efficacy of Ketamine Gargle in Attenuating Postoperative Sore Throat

Sharma¹,

Vaidya

Chand

2015

J Lumbini Med Coll

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“…Nyeri tenggorok pascaoperasi terjadi karena iritasi dan juga inflamasi lokal akibat trauma pada saat laringoskopi dan pemasangan pipa endotrakeal di daerah faring, laring, dan juga trakea. [1][2][3][4][5] Angka kejadian POST setelah pemasangan pipa endotrakeal (ETT) ialah 6-76%. Walaupun POST merupakan komplikasi ringan, namun memberikan kontribusi terhadap morbiditas pascaoperasi, kepuasan pasien, dan merupakan efek samping yang sering dikeluhkan pasien pada periode pascaoperasi.…”

Section: Pendahuluanunclassified

“…[1][2][3] Beberapa tindakan nonfarmakologi yang dapat dilakukan adalah menggunakan pipa endotrakeal dengan ukuran yang lebih kecil, pemberian jeli pelicin yang larut dalam air pada ETT, insersi ETT ke saluran napas dengan hati-hati, melakukan intubasi setelah benarbenar relaks, melakukan pengisapan lendir di daerah orofaring dengan hati-hati, melakukan ekstubasi setelah balon ETT dipastikan sudah kempis, mempertahankan tekanan balon ETT kurang dari 30 mmHg, dan penggunaan pipa endotrakeal low-pressure cuff. 1,[3][4][5] Beberapa metode farmakologi yang dapat dilakukan adalah dengan memberikan inhalasi beklometason, pemberian steroid topikal pada balon ETT, injeksi deksametason intravena, inhalasi flutikason propionat, kumur-kumur dengan azulen sulfonat, kumur-kumur dengan non-steroidal antiinflammatory drug (NSAID) seperti aspirin dan benzidamin hidroklorida, kumur-kumur memakai antagonis reseptor N-methyl D-aspartate (NMDA) seperti ketamin sebelum operasi. [1][2][3][6][7][8] Pada penelitian yang menggunakan lozenge Strepsils ® (dibenal 1,2 mg, amilmetakresol 0,6 mg) untuk penatalaksanaan penyakit radang mulut pada 22 pasien dan kasus bedah mulut 20 orang, dilaporkan bahwa Strepsils ® efektif untuk profilaksis dan juga penyembuhan pada peradangan mulut.…”

Section: Pendahuluanunclassified

“…1,[3][4][5] Beberapa metode farmakologi yang dapat dilakukan adalah dengan memberikan inhalasi beklometason, pemberian steroid topikal pada balon ETT, injeksi deksametason intravena, inhalasi flutikason propionat, kumur-kumur dengan azulen sulfonat, kumur-kumur dengan non-steroidal antiinflammatory drug (NSAID) seperti aspirin dan benzidamin hidroklorida, kumur-kumur memakai antagonis reseptor N-methyl D-aspartate (NMDA) seperti ketamin sebelum operasi. [1][2][3][6][7][8] Pada penelitian yang menggunakan lozenge Strepsils ® (dibenal 1,2 mg, amilmetakresol 0,6 mg) untuk penatalaksanaan penyakit radang mulut pada 22 pasien dan kasus bedah mulut 20 orang, dilaporkan bahwa Strepsils ® efektif untuk profilaksis dan juga penyembuhan pada peradangan mulut. Penelitian lain dilakukan terhadap 272 pasien dengan penyakit inflamasi atau infeksi oral, didapatkan penyembuhan lebih cepat 30% dan nyeri serta fungsi 30% lebih baik.…”

Section: Pendahuluanunclassified

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Pemberian Strepsils® Sebagai Lozenge Praoperasi untuk Mengurangi Nyeri Tenggorok Pascaintubasi Pipa Endotrakeal

Priyonggo¹,

Suwarman²,

Nawawi³

2014

jap

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AbstrakNyeri tenggorok pascaoperasi atau post operative sore throat (POST) terjadi karena iritasi dan inflamasi lokal di daerah faring, laring, dan trakea akibat trauma pemasangan pipa endotrakeal. Penelitian ini bertujuan mengetahui efek tablet hisap Strepsils ® untuk mengurangi POST pada pasien yang dilakukan anestesi umum dengan intubasi pipa endotrakeal. Penelitian dilakukan di Rumah Sakit Dr. Hasan Sadikin Bandung selama bulan Oktober-November 2013, terhadap 66 pasien status fisik American Society of Anesthesiologist (ASA) I-II secara prospektif single blind randomized controlled trial. Pasien dibagi menjadi dua kelompok, yaitu kelompok I, sebanyak 33 orang mendapatkan Strepsils ® dan kelompok II, sebanyak 33 orang mendapatkan plasebo. Pasien diminta untuk mengulum permen sebelum induksi. Data dianalisis dengan uji-t, uji chikuadrat, dan Uji Mann-Whitney. Keluhan POST lebih banyak terjadi pada kelompok II dibandingkan dengan kelompok I. Secara statistik pada T0 didapatkan hasil perbedaan yang bermakna (p<0,05). Pada kelompok II, POST dengan skor 1 sebesar 14 (42%) kasus, dibandingkan dengan kelompok I sebesar 3 (9%) kasus dan tidak ada skor 2. Pada T2 didapatkan hasil perbedaan bermakna (p<0,05), POST sebesar 11 (33%) pada kelompok II, sedangkan kelompok I didapatkan 2(6%) kasus. Pada T4 didapatkan perbedaan tidak bermakna (p>0,05), POST pada kelompok II sebesar 3 (9%) kasus, sedangkan kelompok I skor 1 sebesar 1 (3%) kasus. Simpulan, pemberian Strepsils ® praoperasi dengan anestesi umum mengurangi kejadian dan derajat POST. Strepsils® as Pre-operative Lozenge to Attenuate Post-endotracheal Tube Intubation Related Sore Throat AbstractPost-operative sore throat (POST) is caused by local inflammation and irritation at pharynx and larynx due to traumatic endotracheal tube installation. Sixty six patients, ASA I-II, who underwent elective surgery under general anesthesia and installation of endotracheal tube were enrolled in this single blind randomized controlled trial. Patients were randomly allocated into two groups of 33 subjects: receiving Lozenge and receiving placebo. Designated as Group I (Strepsils® group) and Group II (Placebo group). Patients were asked to suck the candy slowly in the mouth before the induction of anesthesia. Data were analyzed with t-test, Chi-square test and Mann-Whitney test using SPSS ver. 13 program for Windows. The results were POST 9.1% and 42.4% at T0, 6.1% and 33.3% at T2 for Strepsils® and Placebo groups, respectively, which were statistically significant (p<0.05). In T4 and T24, non-significant differences were found (p>0.05).In conclusion, dissolving Strepsils® slowly in the mouth before induction of anesthesia pre-operatively reduces POST following general anesthesia.

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“…Incidences of post-operative sorethroat (POST) are reported to vary from 28% to as high as 80%. [1][2][3][4][5] In a study conducted by Macario et al in 999, patients rated Postoperative sore throat (POST) as their 8 th most undesirable experience in the post-operative period [6] . Increased hospital stay periods and delayed discharges in daycare cases have also been attributed to development of post-operative sore throat [6] .…”

Section: Introductionmentioning

confidence: 99%

Intravenous Ketorolac Tromethamine for Prevention of Postoperative Sore Throat

Nanda¹,

Dalai²,

Mishra³

2017

AIMDR

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Background: Postoperative sore throat is a complication associated with endotracheal intubation. Many pharmacological methods have been employed to treat and prevent it. Ketorolac has been shown to be effective for treatment of pain of surgery. Here we have tried to study its efficacy in prevention of sore throat caused by endotracheal intubation. Methods: With permission from the ethics committee, a double blind random study was conducted on forty consenting adult patients of both sexes belonging to ASA I or II. They were divided into two groups K and C containing twenty each. Group K patients were given Inj. Ketorolac intravenously 10 minutes before induction. Group C was the control group. Both the groups were premedicated with Inj. Glycopyrrolate, Inj. Midazolam and Inj. Pentazocin; induced with Inj. Propofol and intubated following Inj. Vecuronium. At the end of surgery muscle paralysis was reversed with Inj. Neostigmine combined with Inj. Glycopyrrolate. The incidence of sore throat and severity were graded at 0,2,6 and 24 hours following recovery from anaesthesia with the help of Verbal Rating Scale and statistical analysis was done. Results: Ketorolac decreases post-intubation sore throat. Incidences of sore throat was 35% after extubation with Ketorolac premedication, which decreased to 5% by 6 hours. Whereas the same was 80% and 45% respectively in the control group with 35% still suffering from sore throat 24hrs post-operatively. The severity of sore throat ranged from mild to moderate in Group K patients, but varied from mild to severe in the control group. Ketorolac premedication delayed the demand for postsurgery rescue analgesia. Conclusion: Intravenous premedication with the anti-inflammatory drug Ketorolac tromethamine can prevent sore throat induced by laryngoscopy and endo-tracheal intubation and delay post-surgical analgesic requirements.

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Complaints of sore throat after tracheal intubation

Abstract: Postoperative throat complaints frequently arise after tracheal intubation for general anaesthesia in the first 2 postoperative days, but they are of limited intensity and duration.

Cited by 215 publications

References 21 publications

Efficacy of Ketamine Gargle in Attenuating Postoperative Sore Throat

Efficacy of Ketamine Gargle in Attenuating Postoperative Sore Throat

Pemberian Strepsils® Sebagai Lozenge Praoperasi untuk Mengurangi Nyeri Tenggorok Pascaintubasi Pipa Endotrakeal

Intravenous Ketorolac Tromethamine for Prevention of Postoperative Sore Throat

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