Complementary and integrative medicines for behavioral and psychological symptoms of dementia: Overview of systematic reviews

Kwon, Chan-Young; Lee, Boram

doi:10.1016/j.explore.2022.08.005

Cited by 6 publications

(3 citation statements)

References 62 publications

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“…Through an RCT, Hawkins et al evaluated the effect of aromatherapy on long-COVID-19-related chronic fatigue. It is known that aromatherapy is useful in other conditions such as the treatment of agitation in patients affected by dementia, whilst conflicting results are present for other diseases [22]. Despite the increased risk of bias compared with the previous study (due to limited data on random sequence generation), the finding that the group that inhaled the essential oil blend for two weeks had significantly lower fatigue scores is important both from a general and mental fatigue perspective [15].…”

Section: Discussionmentioning

confidence: 97%

Interventions for Improving Long COVID-19 Symptomatology: A Systematic Review

Veronese

Bonica

Cotugno

et al. 2022

Viruses

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Introduction: Although the understanding of several aspects of long COVID-19 syndrome is increasing, there is limited literature regarding the treatment of these signs and symptoms. The aim of our systematic review was to understand which therapies have proved effective against the symptoms of long COVID-19. Methods: A systematic search for randomized controlled or clinical trials in several databases was conducted through 15 May 2022. Specific inclusion criteria included: (1) intervention studies, either randomized controlled (RCTs) or clinical trials; (2) diagnosis of long COVID-19, according to the World Health Organization criteria; (3) presence of long COVID-19 for at least 12 weeks after SARS-CoV-2 infection. Results: We initially found 1638 articles to screen. After removing 1602 works based on their title/abstract, we considered 35 full texts, and among them, two intervention studies were finally included. The first RCT focused on the greater improvement of treatment combining olfactory rehabilitation with oral supplementation with Palmitoylethanolamide and Luteolin in patients with olfactory dysfunction after COVID-19. The second study evaluated the positive impact of aromatherapy vs. standard care in adult females affected by fatigue. Conclusion: Our systematic review found only two intervention studies focused on patients affected by long COVID-19. More intervention studies are needed to investigate potentially positive interventions for long COVID-19 symptoms.

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Section: Discussionmentioning

confidence: 97%

Interventions for Improving Long COVID-19 Symptomatology: A Systematic Review

Veronese

Bonica

Cotugno

et al. 2022

Viruses

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“…In a review paper entitled "Complementary and integrative medicines for behavioral and psychological symptoms of dementia", 13 papers were reviewed [37]. Although aromatherapy was the most common of the alternative therapies, herbal medicine, acupuncture, mindfulness, relaxation, and tai chi were also effective.…”

Section: Interventions For Dementia Disordersmentioning

confidence: 99%

Dementia Disorders: A Narrative Review

Field

2024

J Clin Psychol Neurol

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This narrative review of research includes summaries of 40 papers on dementia disorders that were published during 2023. The publications of this period are primarily randomized controlled trials and systematic reviews/ meta-analyses of randomized controlled trials. A few of these are focused on the prevalence of dementia which approximated one per cent of the world’s population. Only a few studies focused on effects of dementia disorders including memory loss, discrimination, pain, depression and suicidality. Most of the studies addressed predictors of dementia disorders including neurotic personality, frequent tv/computer use and excessive exposure to metals. Loss of short-term memory and other negative experiences including negative life events, loneliness, stress and depression were also significant predictor variables in this recent literature. Physical conditions that were predictive of dementia included pain, hypertension, atrial fibrillation, multi-morbidities, inflammation, encephalitis and neuropathology. Potential underlying mechanisms included dysfunctional neurotransmitter systems (serotonergic, noradrenergic and dopaminergic) and gray matter loss in prefrontal, temporal and other regions associated with memory. Several research groups reported on effective interventions including a Mediterranean diet, plant-based diets, medicinal plants, psychedelics, second generation antidepressants, blood pressure medication, music therapy, aromatherapy and other alternative therapies. Methodological problems relate to the variability in the assessments of dementia disorders, the self-report measures and the cross-sectional data that are not definitive about directionality of predictors and effects of dementia disorders.

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“…The autonomic nervous system may be activated, and the limbic system and hypothalamus may be induced to react through the absorption of essential oil via transdermal administration or inhalation [110]. Therefore, this therapeutic intervention is expected to promote a sense of calmness and reduce restlessness in individuals diagnosed with dementia [111]. Lavender and lemon balms are frequently employed in aromatherapy as essential oils.…”

Section: How Effective Is Aroma Therapy In Vad Patients?mentioning

confidence: 99%

Unravelling the Threads: A Brief Insight into Vascular Dementia

Omar

2023

JVD

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Vascular dementia (VaD), characterized by cognitive decline attributable to cerebrovascular disease, is the second most common type of dementia after Alzheimer’s disease. This review aims to explore the prevalent risk factors, pharmacological interventions, and non-pharmacotherapeutic strategies associated with the condition. Recognized risk factors include advanced age, hypertension, diabetes mellitus, obesity, and hyperlipidemia with emerging evidence implicating additional lifestyle and genetic factors. Pharmacotherapy for VaD mainly focuses on managing these underlying risk factors, coupled with symptomatic treatments. Therapeutic agents commonly used include antihypertensives, statins, antiplatelet drugs, antidiabetic agents, and specific cognitive enhancers like cholinesterase inhibitors. However, the effectiveness of these treatments remains under continuous study, underscoring the need for comprehensive, individualized treatment plans. Non-pharmacotherapeutic strategies, encompassing lifestyle modifications such as diet and exercise have gained considerable attention. They have shown promise in improving cognitive function and enhancing the quality of life in patients with VaD. The application of a multi-domain intervention approach may provide a more holistic management strategy for VaD. Further research is needed to define the best practices in both pharmacotherapy and non-pharmacotherapy treatments, considering the multifactorial and heterogeneous nature of this condition.

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Complementary and integrative medicines for behavioral and psychological symptoms of dementia: Overview of systematic reviews

Cited by 6 publications

References 62 publications

Interventions for Improving Long COVID-19 Symptomatology: A Systematic Review

Interventions for Improving Long COVID-19 Symptomatology: A Systematic Review

Dementia Disorders: A Narrative Review

Unravelling the Threads: A Brief Insight into Vascular Dementia

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