Complete and incomplete Kawasaki disease: two sides of the same coin

Abstract

Complete and incomplete KD appear to be different sides of the same coin, differing only in the number of signs and symptoms at presentation. Similar laboratory findings and coronary artery outcomes between the two groups support this conclusion.

Clinical Profile of Kawasaki Disease (KD) in Children admitted at Dhaka Shishu Hospital

“…This distribution of clinical signs was reported that in the previous studies. 16,21 In our study as well, these changes were also less commonly observed in incomplete KD. In the present study gastrointestinal symptoms, sterile pyuria and arthralgia were found as non-classical signs which are consistent with the findings of Yun et al and Manlhiot et al who demonstrated abdominal pain, vomiting, diarrhea, and Majority of the children had raised WBC (75%), raised ESR (95%), increased platelet count (70%) and elevated CRP (75%).…”

“…15 However, this proportion is higher compared to the incidence (20%) reported by several other studies. 16 Published AHA guidelines, including supplementary laboratory criteria as well as the use of echocardiography, result in better recognition of KD. 17 Regarding patients' age and sex, our study showed the similar complete and incomplete KD groups (p = 0.450 and 0.535 respectively) as compared to that with the findings of Gorczyca et al (2014).…”

“…arthralgia, to be the common non-classical signs. 16,22 Published studies have shown that incomplete KD is associated with higher risk of developing coronary abnormalities. 23 In the present study out of 6 (30%) patients with cardiovascular complications, 3 had complete and 3 incomplete KD.…”

Risk of coronary artery involvement in Kawasaki disease

“…Sudo et al 5,8 indicated the presence of CAD in an echocardiography as a mandatory criterion for incomplete KD, so 100% of cases of incomplete KD had CAD. Manlhiot et al 5,9 defined incomplete KD as fever for ≥5 days and 2 or 3 of the standard criteria, disregarding echocardiographic findings. A similar CAD incidence was found in patients with complete KD.…”

Cardiac complications in children with Kawasaki disease in our own experience

“…Incomplete Kawasaki disease is defined as fever lasting 5 days but accompanied by less than 4 diagnostic signs [9]. Atypical Kawasaki disease is diagnosed in a patient who fulfils the diagnostic criteria if the overall clinical presentation is not typical for Kawasaki disease, e.g.…”