Complete Genital Prolapse with Cervix Carcinoma: A Case Report and Literature Review

Abstract

Background: Although genital prolapse and carcinoma of the uterine cervix are not rare event, their association is very uncommon. We report a case of this association.Case presentation: A-79-year-old female presented with 11 months history of post-menopausal bleeding, pelvic pain and sensation of heaviness which was increasing in intensity over than 8 months. Physical assessment showed a large genital prolapse third degree and ulcerous and necrotic lesion at the lower part prolapse. Histopathological examination of cervical biopsies revealed well differentiated and invasive squamous cell carcinoma. She was staging according to the International Federation of Gynecology and Obstetrics staging system 2009 as FIGO IIIB. The patient was treated by palliative chemotherapy. After 3 months, the patient died. Conclusion:Genital prolapse with cervical carcinoma is a rare association. In fact, it is necessary to individualize the optimal treatment for each patient to improve life quality and the prognosis.

Cervical Cancer in Case with Pelvic Organ Prolapse (POP) and Stress Urinary Incontinence (SUI)

“…There are many treatment modalities for POP, include pessary, reconstructive pelvic surgery with mesh, sacral colpopexy, colocalizes [10] and autologous tissue repair [11]. Treatment options that were reported of the complex comorbidities in recent years include pessary followed by perineorrhaphy and chemoradiotherapy [12], vaginal hysterectomy with pelvic node dissection followed by radiation therapy [13], total vaginal hysterectomy, trans ventral cancer staging and intraabdominal uterosacral ligament suspension [14], radical hysterectomy and immediate sacral colpopexy with an autologous fascia Lata (RISA) graft [15], even palliative chemotherapy (combined terminal cervical carcinoma) [16]. However, the surgical-based treatment in our index patient seemed to be a more favorable treatment strategy.…”

Laparoscopic radical hysterectomy and tension-free vaginal tape-obturator (TVT-O) combined to treat cervical cancer complicating pelvic organ prolapse (POP) and stress urinary incontinence (SUI): A case report

“…Secondly, tumor regression and organ motion can affect the radiation dose, and cystorectocele may increase the risk of visceral radiation injury that lowers QOL if we choose radiotherapy or concurrent chemoradiotherapy, although it may be less invasive [15]. Finally, surgery-based treatment may have a positive effect on survival outcome according to the past two systematic reviews [4,17]. Therefore, it is pivotal to gain the availability of surgical opportunities.…”

Laparoscopic Radical Hysterectomy and Tension-Free Vaginal Tape-Obturator (TVT-O) Combined to Treat Cervical Cancer Complicating Pelvic Organ Prolapse (POP) and Stress Urinary Incontinence (SUI): A Case Report

“…There are many treatment modalities for POP, include pessary, reconstructive pelvic surgery with mesh, sacral colpopexy, colpocleisis [7] and autologous tissue repair [8]. Treatment options that were reported of the complex comorbidities in the recent years included a pessary using followed by perineorrhaphy and chemoradiotherapy [9], vaginal hysterectomy with pelvic node dissection followed by radiation therapy [10], total vaginal hysterectomy, transventral cancer staging and intraabdominal uterosacral ligament suspension [11], radical hysterectomy and immediate sacral colpopexy with an autologous fascia lata (RISA) graft [12], even palliative chemotherapy (combined terminal cervical carcinoma) [13]. However, the surgical-based treatment in our index patient seems to be a more favorable treatment strategy.…”