Complete Genome Sequence of a Virulent Newcastle Disease Virus Strain Isolated from a Clinically Healthy Duck ( Anas platyrhynchos domesticus ) in Pakistan

Abstract

Here, we report the complete genome sequence of a virulent Newcastle disease virus (vNDV) strain, duck/Pakistan/Lahore/AW-123/2015, isolated from apparently healthy laying ducks (Anas platyrhynchos domesticus) from the province of Punjab, Pakistan. The virus has a genome length of 15,192 nucleotides and is classified as member of subgenotype VIIi, class II.

Molecular and virological characterization of the first poultry outbreaks of Genotype VII.2 velogenic avian orthoavulavirus type 1 (NDV) in North‐West Europe, BeNeLux, 2018

“…This VII.2 subgenotype emerged around 2010 in the Middle East and Asia, spreading westward from Indonesia and Pakistan, to Israel and Eastern Europe (Fuller et al., 2017 ; Miller et al., 2015 ; Munir, et al., 2012 ; Rehmani et al., 2015 ; Shabbir et al., 2013 ; Xiao et al., 2012 ). It continued to circulate in the Middle East region (Ghalyanchilangeroudi et al., 2018 ; Munir et al., 2012 ; Pandarangga et al., 2016 ; Wajid et al., 2016 ). VII.2 vAOAV has a wide host range, including Galliformes species, such as chickens, pheasants and peafowls, as well as parakeets and wild birds, such as ducks, geese and pigeons (Munir, et al., 2012 ; Shabbir et al., 2012 ).…”

Complete Genome Sequence of a Velogenic Newcastle Disease Virus Strain Isolated from a Clinically Healthy Exotic Parakeet ( Melopsittacus undulatus ) in Pakistan

“…An NDV isolate designated parakeet/Pak/R-Pindi/SFR-16/2016 (SFR-16) was identified and classified as a member of the newly emerging subgenotype VIIi in poultry production facilities and pet birds in Pakistan. Viruses classified in this subgenotype are widely spread through Asia, the Middle East, eastern European countries, like Turkey, Georgia, Bulgaria, and recently in Indian peafowl causing outbreaks of virulent NDV (vNDV) with high mortality in poultry flocks, suggesting the existence of a fifth panzootic ( 6 – 8 ). Nonsignificant changes in the complete genome sequences of ND viruses recently reported in chickens, ducks and parakeets in Pakistan revealed apparent spill-over of the viruses among them ( 7 ).…”

Genetic evolution of class I Newcastle disease virus from poultry at live bird markets in Eastern China

“…Based on the genome size and phylogenetic analysis of the F gene, NDV can be divided into two groups: class I and class II [3]. Class I is exclusively avirulent and can be subdivided into nine genotypes (1)(2)(3)(4)(5)(6)(7)(8)(9). In comparison, class II is subdivided into eighteen genotypes (I-XVIII) based on the partial sequence of the F gene (47-420 nt).…”

“…Waterfowl, the natural reservoir of NDVs, has the potential to spread the virus in the environment and within their susceptible hosts. It results in frequent ND outbreaks and subsequent economic losses [8][9][10]. Class I NDVs were originally recovered from both domestic and wild birds sampled in North America and Eurasia since at least the 1970s [6,11,12].…”