Complete Genome Sequence of Klebsiella pneumoniae Siphophage Skenny

Gramer, Jacob; Kenny, Sarah E.; Newkirk, Heather; Liu, Mei; Gill, Jason J.; Ramsey, Jolene

doi:10.1128/mra.01036-19

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2019

2024

Publication Types

Select...

Article1

Preprint1

Relationship

Self Cite1

Independent1

Authors

Journals

Cited by 2 publications

(1 citation statement)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…than 83% overall nucleotide identity (E value ϭ 0) with a group of characterized T1-like Klebsiella phages, including Sushi (GenBank accession no. KT001920) (19), Skenny (MK931444) (20), Sweeny (MK931443) (21), and Shelby (MK931445) (22). The Sanco genome was opened to be syntenic with those of phage T1 (NC_005833) and phage TLS (NC_009540).…”

mentioning

confidence: 99%

Complete Genome Sequence of Klebsiella pneumoniae Siphophage Sanco

Richardson

Lessor

O’Leary

et al. 2019

Microbiol Resour Announc

Self Cite

View full text Add to dashboard Cite

show abstract

mentioning

confidence: 99%

Complete Genome Sequence of Klebsiella pneumoniae Siphophage Sanco

Richardson

Lessor

O’Leary

et al. 2019

Microbiol Resour Announc

Self Cite

View full text Add to dashboard Cite

show abstract

Weberviruses are gut-associated phages that infectKlebsiellaspp

Dawson,

Shibu,

Garnett

et al. 2024

Preprint

View full text Add to dashboard Cite

Weberviruses are bacteriophages (phages) that have been shown to infect and lyse members of the genusKlebsiella. Due to their antimicrobial properties, phages and their products have emerged as a potential therapeutic option to help tackle increasing rates of antimicrobial resistance amongstKlebsiellaspp. Weberviruses are an attractive option due to their high burst sizes, long shelf life and associated depolymerase enzymes. In this study we isolated and characterized seven new weberviruses and compared their genomes with those of their closest relatives to further our understanding of the genusWebervirus. We show that the seven phages isolated in this study can lyse a range of clinical multidrug-resistantKlebsiellastrains, includingK. variicola. Gene-sharing network-based analysis using vConTACT2 and incorporating all publicly available webervirus genomes (n=67) confirmed the seven phages as members of the genusWebervirusand that weberviruses are affiliated with the familyDrexlerviridae. Using the online resource PhageClouds, we demonstrated that weberviruses can be readily detected in metagenome-derived phage datasets from a diverse range of geographical locations. Using a curated database of 67 isolated phage genomes and 60 metagenome-assembled genomes (n=127 total), we found that weberviruses are primarily associated with samples originating from the gut, with human faeces (61/127, 48 %), sewage (39/127, 31 %) and wastewater (14/127, 11 %) being the most frequent sources of these phages.

show abstract

Complete Genome Sequence of Klebsiella pneumoniae Siphophage Skenny

Cited by 2 publications

References 21 publications

Complete Genome Sequence of Klebsiella pneumoniae Siphophage Sanco

Complete Genome Sequence of Klebsiella pneumoniae Siphophage Sanco

Weberviruses are gut-associated phages that infectKlebsiellaspp

Contact Info

Product

Resources

About