2006
DOI: 10.1097/01.smj.0000197039.06853.f0
|View full text |Cite
|
Sign up to set email alerts
|

Complete Heart Block and Cardiac Tamponade Secondary to Merkel Cell Carcinoma Cardiac Metastases

Abstract: This is a unique case of Merkel cell carcinoma, a rare neuroendocrine tumor, metastasizing to the heart and inducing a progression of cardiac complications such as new-onset atrial fibrillation, malignant pericardial effusion with tamponade physiology, first-degree heart block, and complete heart block. Metastases to the heart are relatively rare but should be suspected if a patient with a known neoplasm presents with new cardiac manifestations. This is the first case report of cardiac metastases from Merkel c… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

1
5
0

Year Published

2006
2006
2022
2022

Publication Types

Select...
8

Relationship

0
8

Authors

Journals

citations
Cited by 10 publications
(6 citation statements)
references
References 14 publications
1
5
0
Order By: Relevance
“…Contrary to what was observed in the autopsy series, all patients in our cohort had endocardium lesions. Both within our series and previously reported cases, the predominance of endocardial lesions involved in the right side of the heart supports the hypothesis that cardiac mMCC disseminates via hematogenous spread [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ]. The predilection of the right atrium/ventricle may be a characteristic feature of cardiac metastasis in MCC.…”
Section: Discussionsupporting
confidence: 91%
See 2 more Smart Citations
“…Contrary to what was observed in the autopsy series, all patients in our cohort had endocardium lesions. Both within our series and previously reported cases, the predominance of endocardial lesions involved in the right side of the heart supports the hypothesis that cardiac mMCC disseminates via hematogenous spread [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ]. The predilection of the right atrium/ventricle may be a characteristic feature of cardiac metastasis in MCC.…”
Section: Discussionsupporting
confidence: 91%
“…There were 14 unique patients with cardiac mMCC reported in the published case reports between 1990 to 2019 ( Table 4 ) [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ]. The median age at diagnosis was 67.5 years (range 23–82 years) with a male predominance (male 9, female 5).…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…5 Cardiac metastases from all tumors are relatively common, and autopsy series show a range of 8% to 12%. 10,11,12 There are no randomized controlled trials for the management of Merkel cell carcinoma. 8 Extramedullary plasmacytoma of the heart is rare, and few cases have been reported in the literature.…”
Section: Diagnosis In Oncologymentioning
confidence: 99%
“…While infrequent overall, since 2001, many cases of cardiac metastasis of MCC have been reported in the literature, with clinical consequences including symptoms of chest pain and shortness of breath, various degrees of heart block, and malignant pericardial effusion with resultant tamponade [ 28 33 ]. With an additional complication of acute kidney injury, the scattered cardiac metastases observed on autopsy probably drove the acute hypertroponinemia observed in this patient's case, as has been observed in other head and neck cancers metastatic to the heart.…”
Section: Discussionmentioning
confidence: 99%