Lumbar sympathectomy is indicated for the treatment of intermittent claudication or rest pain in legs due to ischemia of Buerger's disease, chronic regional pain syndrome (CRPS) type I,II, thromboembolic phenomena, diabetic ulcers, diabetic neuropathic pain, acute herpes pain, Paget's disease of bones, hyperhidrosis, chronic pancreatitis and malignant visceral pain.Buerger's disease is an inflammatory disorder affecting medium sized vessels and adjacent nerves where tobacco plays key role for the disease process. Major presenting symptoms are moderate to severe pain in the limbs, affection of sleep and significant work disability. On Doppler ultrasonography there is reduced/absent flow in peripheral arterial system usually in iliofemoral, popliteal, tibialis posterior and dorsalis pedis artery in patients with ischemic lower limb. Lumbar sympathetic ganglia are present from L2 to L5 paravertebral region where blocking of L2-L3 ganglia blocks the sympathetic fibres of the lower extremities and produces vasodilatation. There are surgical and nonsurgical options available for the treatment of ischemic pain and non-healing ulcers.