“…4,6 Various treatments, such as rhytidoplasty, rhytidectomy, and botulinum toxin injections, have been described in the literature. [7][8][9] Two cases involving frontal region treatment associated with the use of tissue expanders prior to frontal rhytidoplasty have also been reported. 9,10 A search was performed of the PubMed and Embase databases using the following terminology: pachydermoperiostosis, "Touraine Solente and Golé Syndrome," treatment, surgical treatment, frontal lifting, subperiosteal lifting, tissue expander, and combinations of these.…”