Complete spontaneous resolution of a giant bulla without rupture or infection: a case report and literature review

Chang, Won Ho

doi:10.21037/jtd.2017.05.53

Cited by 10 publications

(3 citation statements)

References 7 publications

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“…4,6 The time course of bulla evolution appears highly variable with multiple reports of bullae developing over days while in other cases, bullae remain stable for years or resolve spontaneously. 3,[7][8][9] There are multiple proposed mechanisms of bullae formation. In emphysema, bullae may result from the same connective tissue-destroying processes associated with the development of emphysema.…”

Section: Discussionmentioning

confidence: 99%

Enlarging bullae and spontaneous pneumothorax associated with CPAP use: A case series of three patients

Navarrete-Welton,

Manzoor,

Minami

et al. 2024

JMV

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Objectives Spontaneous pneumothorax among patients with obstructive sleep apnea treated by nocturnal continuous positive airway pressure (CPAP) has not been well documented. Methods We present three cases of patients on chronic CPAP who experienced spontaneous pneumothorax without clear predisposing factors. Their personal and family medical histories, imaging characteristics, and CPAP settings are reviewed. Results In all three cases, the patients had bullae ipsilateral to the pneumothoraces that either formed (n = 1) or grew significantly (n = 2) after CPAP initiation. No other risk factors for pneumothorax or bullae were identified. Conclusions This case series demonstrates a need for further investigation into a possible connection between spontaneous pneumothorax, bullae development, and CPAP use. Keywords: obstructive sleep apnea, continuous positive airway pressure, bullae, complications of noninvasive mechanical ventilation, spontaneous pneumothorax

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Section: Discussionmentioning

confidence: 99%

Enlarging bullae and spontaneous pneumothorax associated with CPAP use: A case series of three patients

Navarrete-Welton,

Manzoor,

Minami

et al. 2024

JMV

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“…Lung bullae are best detected on CT imaging as it gives more description on the number, size, and position [ 8 ]. Spontaneous resolution has been reported in previous literature though it is rare [ 9 ]. Eventually, bullectomy is recommended in symptomatic patients with giant lung bulla [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

Loss of consciousness during air travel: A case of lung bullae

Bosco

Sadiq

et al. 2021

Oxford Medical Case Reports

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A giant lung bulla occupies at least a third of the lung space. We present a middle-aged man who lost consciousness during an air flight for 30 minutes, without any respiratory symptoms. An incidental finding on chest x-ray revealed a giant bulla and a chest computed tomography imaging confirmed the diagnosis and ruled out a tension pneumothorax. A giant lung bulla is an uncommon cause of loss of consciousness and may be suspected if it occurs during air travel.

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“…Several factors have been associated with GBE, such as cigarettes, inhaled drug abuse, alpha-1 antitrypsin deficiency, and connective tissue diseases (e.g., Marfan syndrome and Ehlers-Danlos syndrome), with the most common type related to cigarette use and resultant chronic obstructive pulmonary disease (COPD) [4][5].…”

Section: Introductionmentioning

confidence: 99%

Differentiating Giant Bullous Emphysema From Tension Pneumothorax: A Case Report

Ascano,

Kramer,

2024

Cureus

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Giant bullous emphysema (GBE) is a progressive disease that commonly presents with severe progressive dyspnea attributed to the progressive destruction of alveolar walls and the formation of large air pockets, resulting in impaired gas exchange. This presentation is most commonly seen in young, thin male smokers. GBE poses an interesting and unique clinical challenge due to its radiologic findings, which can be easily mistaken for tension pneumothorax. Despite the decreased acuity of GBE as compared to tension pneumothorax, inadequate treatment in a severe case can lead to spontaneous pneumothorax, infection, and/or respiratory failure. In this report, we highlight a case of severe GBE that presents similarly to tension pneumothorax in both symptomatology and radiologic findings. The case at hand is of a 50-year-old male patient with a history of chronic obstructive pulmonary disease (COPD) with complaints of dyspnea and subsequent findings of tachycardia, tachypnea, and hypoxemia with significantly decreased breath sounds in the right lung. Radiologic findings showed increased lucency of the right hemithorax and a mass effect with a mediastinal shift to the left. History and further imaging with CT led to an ultimate diagnosis of severe GBE and COPD exacerbations. The patient was treated with non-invasive medical management. With the challenges of overlapping presentations, landing on the correct diagnosis is imperative to accurately and adequately treat the patient since GBE and tension pneumothorax significantly differ in acuity and overall management, hence the need for a high level of suspicion based on the clinical picture and the use of high-resolution CT.

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Complete spontaneous resolution of a giant bulla without rupture or infection: a case report and literature review

Cited by 10 publications

References 7 publications

Enlarging bullae and spontaneous pneumothorax associated with CPAP use: A case series of three patients

Enlarging bullae and spontaneous pneumothorax associated with CPAP use: A case series of three patients

Loss of consciousness during air travel: A case of lung bullae

Differentiating Giant Bullous Emphysema From Tension Pneumothorax: A Case Report

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