“…Appropriate antibiotics can be selected aiming to manage the Staphylococcus aureus and Gram-negative organisms as these are the most common organisms, later can be changed to the antibiotics based on culture and sensitivity patterns [16,30,47,50,51]. It is of utmost importance to anticipate the potential risk of CSF leak and take adequate measures to repair the defects in bone and remove the foreign bodies [1,6,[52][53][54]. The complications can be potentially prevented by appropriate and timely management interventions including careful and thorough irrigation of the wound to remove contaminated bone and tissue fragments and any foreign bodies [30,35].…”