“…bagging, boosting or random forests, see Chapter 11 of Volume 1) has been particularly studied in this context [Yang et al, 2010]. It has been applied to various problems and showed interesting results each time, either for gene or protein expression data [Liu et al, 2010;Piao et al, 2012;Wu et al, 2003;Gertheiss and Tutz, 2009], the prediction of regulatory elements [Gordon et al, 2005;Wang et al, 2009;Lihu and Holban, 2015] and a large range of other applications such as the analysis of interaction data [Nagi et al, 2017], protein structure prediction [Bouziane et al, 2015] or automatic function annotation [Schietgat et al, 2010;Galiez et al, 2016;Yang et al, 2016a;Smitha and Reddy, 2016].…”