Medical information systems (MIS) are the object of the research presented. They allow information processing throughout the patient's interaction with medical services - from contacting such institutions to monitoring the patient after rehabilitation. However, for various reasons, during the information process exchange within the framework of MIS, distortions of collected or transmitted data are possible, which leads to wrong medical decisions. Currently, new approaches are being implemented using Software-Defined Networks, but our work proposes an alternative solution designed to work conservatively with existing equipment using established protocols. To solve the stated problem, this study has developed a universal hardware-software module (UHSM) model, which ensures the effective transmission of sophisticated medical information through networks. A distinctive feature of such UHSM is the connection of different medical equipment in various related to MIS information networks, as well as automatic configuration under all current standards. The study demonstrates that for the most effective UHSM functioning, it is essential to consider the existing features arising during the interaction process of devices in the context of modern networks created for information exchange, based on the established communication model of open-system interconnection (OSI). Keywords—classification methods, information coding methods, information networks, knowledge base, medical information system, multilevel approach, structure synthesis of large systems, telemedicine technologies