A common clinical constellation of pain, sensory, autonomic, motor, or trophic symptoms that can no longer be attributed to the initial trauma characterizes Complex Regional Pain Syndrome (CRPS). These signs and symptoms are not localized to the areas of innervation. Most of the diagnosis is clinical. Following that, mobility difficulties, fluctuating skin temperature, sensory loss and changes in body perception are the prominent symptoms. In acute phases, pharmaceutical treatment may be very beneficial. Empirically, common anti-neuropathic pain medications can be suggested. Physical and occupational therapy, as well as behavioral therapy, are crucial parts of the treatment.