Complexes of glucose oxidase with chitosan and dextran possessing enhanced stability

Baykal, Ecem; Vardar, Gokay; Attar, Azade; Yapaöz, Melda Altıkatoğlu

doi:10.1080/10826068.2020.1719515

Cited by 2 publications

(1 citation statement)

References 28 publications

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“…Macromolecular crowding, which is the natural environment of enzymes in vivo, can explain the stabilizing effect of some additives [46][47][48][49]. It can be mimicked in vitro through the addition of high concentrations of macromolecules such as dextran or PEG [50] and would favor the folded state of proteins and compact conformation through the excluded volume effect [51][52][53][54][55]. However, the stabilizing effect of in vitro crowding would not be universal as the properties of all macromolecules in vivo are finely regulated under different physiological conditions [56].…”

Section: Chemical Stabilizer Additionmentioning

confidence: 99%

From Enzyme Stability to Enzymatic Bioelectrode Stabilization Processes

et al. 2021

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Bioelectrocatalysis using redox enzymes appears as a sustainable way for biosensing, electricity production, or biosynthesis of fine products. Despite advances in the knowledge of parameters that drive the efficiency of enzymatic electrocatalysis, the weak stability of bioelectrodes prevents large scale development of bioelectrocatalysis. In this review, starting from the understanding of the parameters that drive protein instability, we will discuss the main strategies available to improve all enzyme stability, including use of chemicals, protein engineering and immobilization. Considering in a second step the additional requirements for use of redox enzymes, we will evaluate how far these general strategies can be applied to bioelectrocatalysis.

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Section: Chemical Stabilizer Additionmentioning

confidence: 99%

From Enzyme Stability to Enzymatic Bioelectrode Stabilization Processes

et al. 2021

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Preparation of Self‐Driven Triboelectric Nanosensor Based on Chitosan‐Coated Ti Foil for Detecting Blood Glucose Concentration

Yao,

Xu,

Zhang

et al. 2024

Adv Eng Mater

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The clinical diagnosis of diabetes mellitus typically depends on blood glucose measurements. Many laboratory studies have focused on enzyme–electrode biosensors that require an external power source. In this study, the potential of triboelectric nanogenerators (TENGs) as self‐driven sensors for glucose detection is investigated by utilizing the glucose specificity of glucose oxidase. When immersed in glucose solutions with concentrations ranging from 3.9 to 13.1 mmol L−1, the TENGs exhibit a linear relationship between the glucose concentration and current and voltage changes. These findings suggest that the TENGs developed in this study can effectively function as glucose sensors, providing a foundation for future human blood glucose monitoring applications and demonstrating a promising new approach for biomedical sensor technology.

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Complexes of glucose oxidase with chitosan and dextran possessing enhanced stability

Cited by 2 publications

References 28 publications

From Enzyme Stability to Enzymatic Bioelectrode Stabilization Processes

From Enzyme Stability to Enzymatic Bioelectrode Stabilization Processes

Preparation of Self‐Driven Triboelectric Nanosensor Based on Chitosan‐Coated Ti Foil for Detecting Blood Glucose Concentration

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