Complexes of vanadium(III) with l-alanine and l-aspartic acid

Vanadium: History, chemistry, interactions with α-amino acids and potential therapeutic applications

“…For example, up to pH ' 4 they are similar to those for L-alanine, but in the higher pH region, it forms mono and various dinuclear species of carboxylic or l-oxo bridges differing from each other by the number of coordinated ligands and OH À groups. Nevertheless, both V(III)-L-aspartic acid and V(III)-L-alanine complexes, have a significant apoptotic effect on Hepatoma Morris 5123 cells [49]. Complex compounds of vanadium(III) with L-histidine (His) instead, showed that solutions at pH 2-4.5, consecutive mononuclear species MLH, ML 2 H 2 , MLH 2 , ML 2 H 4 and ML are formed, but at higher pH, mixed hydroxy-and/or oxo-species appeared in solution.…”

Preface: Recent Advances and Highlights of the 5th International Vanadium Symposium

“…solution studies of complex formation with the amino acids L-alanine and L-aspartic acid (210) and with L-cysteine and S-methylcysteine (211), and some other systems (202). Globally the stability of the vanadium complexes with amino acids follow the order V(V) < V(IV) < V(III) (211).…”

Synthesis and Characterization of NH4V(Gly)3(PO4)2.H2O

“…Therefore, much of the research on the vanadium coordination chemistry has focused on the area of coordination to amino acids [9][10][11][12][13][14]. There have been numerous reports on the formation vanadium-amino acid complexes in aqueous solution [6,[15][16][17][18].…”