Compliance of the recurrent renal stone former with current best practice guidelines

Bos, Derek; Kim, Kevin; Hoogenes, Jen; Lambe, Shahid; Shayegan, Bobby; Matsumoto, Edward D.

doi:10.5489/cuaj.4605

Cited by 11 publications

(10 citation statements)

References 23 publications

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“…In addition, 67. 1% of patients believed in the efficacy of preventative stone measures and 22.8% of patients perceived their stone disease to be severe [21]. Dauw et al found an adherence rate of 30.3% with preventive pharmacologic therapy in kidney stone patients.…”

Section: Discussionmentioning

confidence: 99%

Patient’s perception of kidney stone prevention within the emergency department and its adherence factors: a single institution study

Moussa

Chakra

2019

BMC Emerg Med

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Background: No known data in the literature assessing practice of kidney stone prevention in the emergency department (ED) is available. Objectives: Assess patient perception and compliance to kidney stone prevention given within the emergency department. It also indirectly detects the attitude and practice patterns of primary care providers in kidney stone prevention. Materials and methods: This is a qualitative study done in a single institution from January 2018 to January 2019 that includes 99 patients that were diagnosed with kidney or ureteral stone in ED and were discharged home, all of them where stone formers. They were asked to fill a self-administered questionnaire when they are able to read, or interviewed by the resident within the ED when they are unable to read. Results: The majority of patients (68%) did not receive any instructions about kidney stones prevention within the ED. Most of patients who follow instructions if it was given were educated (90%), had an insurance coverage (85%), and had an income higher than $1000 per month (76%), (p < 0.05). Seventy one percents of patients believe in the effectiveness of stone prevention if it was provided and most of them are interested in learning about these preventive strategies (82%). Reasons for not following the instructions about kidney stones prevention measures were the cost (53.1%) following by the lack of explanation by ED physicians (18.8%). The majority of patients (62.6%) prefer to receive kidney stones prevention measures from urologists. Conclusion: Most of patients in our institute did not receive kidney stones prevention measures in ED despite that they declared their interest in following these measures. Most of the time they did not adhere to those measures due to socioeconomic factors and lack of clarifications. If these instructions were given within the ED, it could lead to an acceptable compliance rate.

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Section: Discussionmentioning

confidence: 99%

Patient’s perception of kidney stone prevention within the emergency department and its adherence factors: a single institution study

Moussa

Chakra

2019

BMC Emerg Med

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“…This is of outmost importance because even adherence to these nonspecific measures, such as increased fluid intake, salt compliance, and citrate and protein intake is only 45.8%. 22 To the best of our knowledge only two studies were previously published in the literature, both by Dauw and colleagues 23,24 that examined nonadherence and the associated factors in patients with nephrolithiasis. Both studies were based on medical and pharmacy claims data.…”

Section: Discussionmentioning

confidence: 99%

Long-Term Adherence to Medications in Secondary Prevention of Urinary Tract Stones

Golomb

Nevo

Goldberg

et al. 2019

Journal of Endourology

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Purpose: To reduce the high recurrence rate of nephrolithiasis, patients are routinely prescribed secondary chemoprevention therapy with alkali citrate (Alkasolve Ò ; Sam-On Ltd) for uric acid stones and hypocitraturia or hydrochlorthiazide (Disothiazide Ò ; Dexcel Ltd) for hypercalciuria. However, data on adherence to these regimens are limited. The aim of this study was to assess rates of long-term adherence to alkali citrate and hydrochlorothiazide and reasons for nonadherence. Materials and Methods: Patients on follow-up for kidney stone disease at a dedicated tertiary stone clinic, from 2010 to 2016, were asked to complete a telephone survey on adherence to secondary prevention medications and reasons for nonadherence. Compliance was also verified by actual drug distribution as reported through a computerized monitoring system. Results: The cohort included 356 patients with mean age of 58 years, 199 (64% men, 36% women) treated with alkali citrate and 143 (68% men, 32% women) treated with hydrochlorothiazide. Adherence rates were 42% in the alkali citrate group and 52% in the hydrochlorothiazide group (p = 0.05). The main reason for noncompliance in the alkali citrate group (22%) was the number of pills needed to be taken daily. Adverse drug effects were the most common reason for noncompliance in the hydrochlorothiazide group (24%) and in 10% of the alkali citrate group (p < 0.0005). Adherence was poorer in younger patients who did not regularly take other medications than in older patients with other chronic diseases and polypharmacy. Conclusions: About half the patients with clear metabolic abnormalities who were prescribed secondary chemoprevention with hydrochlorothiazide and alkali citrate failed to adhere to the prescribed regimen. Reasons for noncompliance differed between both drugs. The findings of this study may help clinicians to identify patients at risk for nonadherence and suggests potential means to improve compliance rates.

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“…Простая, на первый взгляд, рекомендация по повышению потребления воды на самом деле выполняется не всеми больными [68]. При этом сами больные могут быть уверены и/или уверять своего врача, что потребляют достаточно воды [69].…”

Section: итоги для клинической практикиunclassified

Nephrolithiasis and the risk of myocardial infarction and stroke.

Alfimov¹,

Shaderkin²,

Lebedev³

et al. 2022

ECU

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Introduction. The article discusses the results of studies and meta-analyses that have studied the risks of coronary heart disease (CHD), myocardial infarction (MI) and stroke in patients with urinary stone disease (USD). The purpose of this review is to critically analyze the available studies on the association of USD with CHD and stroke, as well as to evaluate USD among other cardiovascular disease (CVD) risk factors and to assess the role of USD metaphylaxis in reducing this risk. Materials and methods. The authors conducted a search in international and domestic specialized databases of scientific publications, 657 publications were found. For this review, 75 articles were selected that were published no later than April 1, 2021. Results. Despite conflicting research results and high statistical heterogeneity, all meta-analyses have shown that patients with USD have an increased risk of coronary artery disease, MI, and stroke by about 20-40%. In comparison with other risk factors for CVD, USD represents a moderate risk, which dictates not only the need to identify and correct «high» risk factors in patients with USD, but also the need for effective metaphylaxis. There are no studies to support the efficacy of USD metaphylaxis in reducing the risk of CVD. However, it can be assumed that effective metaphylaxis, especially in young patients, using remote technologies, will not only reduce the risk of urolithiasis recurrence, but also help correct metabolic disorders that trigger pathophysiological processes common with CVD. The possibility that simple and inexpensive interventions that reduce the risk of recurrent urolithiasis may also reduce the risk of MI and stroke, the most common cause of death and disability, warrants further study. Conclusions. To increase the effectiveness of USD metaphylaxis, it is possible to use remote monitoring with automatic data processing and regular feedback.

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Compliance of the recurrent renal stone former with current best practice guidelines

Cited by 11 publications

References 23 publications

Patient’s perception of kidney stone prevention within the emergency department and its adherence factors: a single institution study

Patient’s perception of kidney stone prevention within the emergency department and its adherence factors: a single institution study

Long-Term Adherence to Medications in Secondary Prevention of Urinary Tract Stones

Nephrolithiasis and the risk of myocardial infarction and stroke.

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