Compliance with Antibiotic Prophylaxis in Obstetric and Gynecological Surgeries in Two Peruvian Hospitals

Arteaga‐Livias, Kovy; Panduro-Correa, Vicky; Maguiña, Jorge L.; Osada, Jorge; Rabaan, Ali A.; Lijarza-Ushinahua, Kiara; Barboza, Joshuan J.; Gómez, Walter; Rodríguez-Morales, Alfonso J.

doi:10.3390/antibiotics12050808

Cited by 4 publications

(1 citation statement)

References 32 publications

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“…The pooled estimate of antibiotics used by inpatients admitted to obstetrics and gynecology wards of the hospitals in SSA were 46%. The finding of this study was higher than the antibiotic consumption in obstetrics and gynecology departments of Peruvian hospital 31% 79 . Higher antibiotic use in obstetrics and gynecology wards in SSA can be attributed to factors such as a higher prevalence of surgical procedures 80 , which often require prophylactic antibiotics to prevent post-operative infections 81 .…”

Section: Discussioncontrasting

confidence: 58%

Point prevalence of evidence-based antimicrobial use among hospitalized patients in sub-Saharan Africa: a systematic review and meta-analysis

Boltena,

Wolde,

Hailu

et al. 2024

Sci Rep

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Excessive and improper use of antibiotics causes antimicrobial resistance which is a major threat to global health security. Hospitals in sub-Saharan Africa (SSA) has the highest prevalence of antibiotic use. This systematic review and meta-analysis aimed to determine the pooled point prevalence (PPP) of evidence-based antimicrobial use among hospitalized patients in SSA. Literature was retrieved from CINAHL, EMBASE, Google Scholar, PubMed, Scopus, and Web of Science databases. Meta-analysis was conducted using STATA version 17. Forest plots using the random-effect model were used to present the findings. The heterogeneity and publication bias were assessed using the I2 statistics and Egger’s test. The protocol was registered in PROSPERO with code CRD42023404075. The review was conducted according to PRISMA guidelines. A total of 26, 272 study participants reported by twenty-eight studies published from 10 countries in SSA were included. The pooled point prevalence of antimicrobial use in SSA were 64%. The pooled estimate of hospital wards with the highest antibiotic use were intensive care unit (89%). The pooled prevalence of the most common clinical indication for antibiotic use were community acquired infection (41%). The pooled point prevalence of antimicrobial use among hospitalized patients were higher in SSA. Higher use of antibiotics was recorded in intensive care units. Community acquired infection were most common clinical case among hospitalized patients. Health systems in SSA must design innovative digital health interventions to optimize clinicians adhere to evidence-based prescribing guidelines and improve antimicrobial stewardship.

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Section: Discussioncontrasting

confidence: 58%

Point prevalence of evidence-based antimicrobial use among hospitalized patients in sub-Saharan Africa: a systematic review and meta-analysis

Boltena,

Wolde,

Hailu

et al. 2024

Sci Rep

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Effect of patient education on surgical site infections rates: a systematic review of the literature

Michail,

Tsitsi,

Charalambous

2024

International Journal of Healthcare Management

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Assessment of antibiotic utilization and prescribing quality in a teaching hospital in Iraq

Abdullah,

Essa,

Aladul

et al. 2024

Journal of Pharmaceutical Health Services Research

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Objectives This study aimed to assess the prevalence of antibiotic use, quantify antibiotic consumption, and evaluate the quality of prescribing. Methods This was a point prevalence study conducted at a teaching hospital in Mosul, Iraq. The antibiotics prescribing data were retrieved from the medical records of admitted patients between January and February 2023. The trends of utilization of prescribed antibiotics were expressed in defined daily doses per 100 bed days (DDD/100 BD). Key findings The records of 546 patients were checked. Antibiotics were prescribed for 88.46% of admitted patients. The main mode of antibiotic therapy in gynecology and obstetrics (97.59%) and surgical (86.84%) wards was surgical prophylaxis and 54% of these patients received antibiotics for more than 24 hours. The overall antibiotic consumption in the hospital was 135.09 DDD/100 BD. The highest consumption was in the gynecology and obstetrics ward (242.17 DDD/100 BD). Ceftriaxone (73.65 DDD/100 BD) and metronidazole (41.76 DDD/100 BD) were the most frequently prescribed antibiotics for the admitted patients. The internal medicine ward had the highest percentage (94.22%) of Watch-class antibiotic use, while the gynecology and obstetrics ward had the highest percentage (64.53%) of Access-class antibiotic use. Conclusions This study highlighted the high prevalence of antibiotic use, particularly ceftriaxone. Furthermore, the study highlighted the lack of adherence to both national and international guidelines. Urgent action should be undertaken to implement antimicrobial stewardship programs.

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Compliance with Antibiotic Prophylaxis in Obstetric and Gynecological Surgeries in Two Peruvian Hospitals

Cited by 4 publications

References 32 publications

Point prevalence of evidence-based antimicrobial use among hospitalized patients in sub-Saharan Africa: a systematic review and meta-analysis

Point prevalence of evidence-based antimicrobial use among hospitalized patients in sub-Saharan Africa: a systematic review and meta-analysis

Effect of patient education on surgical site infections rates: a systematic review of the literature

Assessment of antibiotic utilization and prescribing quality in a teaching hospital in Iraq

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