Compliance with night-time overcorrection bracing in adolescent idiopathic scoliosis: Result from a cohort follow-up

Laquievre, Antoine; Dolet, Nathan; Laure, Moisson; Colobert, Briac; Mallet, J.-F.; Corinne, Bronfen

doi:10.1016/j.medengphy.2020.01.003

Cited by 16 publications

(16 citation statements)

References 24 publications

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“…About 0.3% population is estimated to suffer with moderate-risk scoliosis. Bracing helps to mitigate an increase in the curvature of the spine and to evade surgery [32]. If this does not serve the purpose, then the doctor will advise the surgery, which can straighten the spine and control the further increase in the curvature.…”

Section: Resultsmentioning

confidence: 99%

3D modeling of human spine and the cobb angle measurement in scoliosis patients

Yang¹,

Baqir²,

Kashif³

et al. 2021

J Clin Images Med Case Rep

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Scoliosis is a disease caused by the abnormal curvature of spine. Generally, curvature above 10 degrees is considered as a scoliosis. About 2-4% of the world population is affected by this disease. Therefore, there is a need for such a tool that can help surgeons and bioengineers to study the behavior of a spine under various conditions. Considering the engineering perspectives, it is necessary to understand the fundamental anatomy of the human spine and pathological techniques associated with the orthopedic conditions, so that better technologies can be implemented. The main objective of this work is to develop a 3D model that can simulate various orthopedic conditions associated with the change in Cobb angle. CT scans of patients are obtained from the Spine center of G. hospital, Lahore. 3D Models of actual patients are created using 3D Slicer and Radiant software. Only spine portions are extracted to understand the type of scoliosis, curvature region, and Cobb angles. The cobb angle of each of the patients is measured using Solid Works software. Considering the real data of patients, the severity level of scoliosis in the patients is discussed. Keywords: anthropometry; Cobb angles; CT scans; scoliosis; Spine deformity; vertebra.

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Section: Resultsmentioning

confidence: 99%

3D modeling of human spine and the cobb angle measurement in scoliosis patients

Yang¹,

Baqir²,

Kashif³

et al. 2021

J Clin Images Med Case Rep

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“…The most common of such devices were temperature and pressure/force sensors. The temperature sensors were proved to be effective to monitor wearing time [2,[10][11][12][13][14][15][16][17][18], but they could not measure the level of wearing tightness. Nicholson et al [10] reported that the mean temperature at the skinbrace interface was 32.8 ± 1.6°C.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, electronic devices were developed to measure medication compliance objectively. The electronic solution can be divided into three categories: temperature-based systems [2,[10][11][12][13][14][15][16][17][18], forcebased systems [19][20][21][22][23][24], and force and temperaturecombined systems [9]. A temperature-based system, with its temperature sensors, can record the brace wearing time (quantity) of the patients accurately, but cannot measure the wearing tightness (quality).…”

Section: Introductionmentioning

confidence: 99%

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A compliance real-time monitoring system for the management of the brace usage in adolescent idiopathic scoliosis patients: a pilot study

Zhu

Xiao

et al. 2021

BMC Musculoskelet Disord

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Background Patient compliance is essential to the effectiveness of brace treatment for adolescent idiopathic scoliosis (AIS) patients. Subjective measurements like questionnaires and inquiries proved to be arguably inaccurate. Although some scholars have applied temperature/force monitors to measuring patient compliance objectively, few studies to date could monitor patient compliance in real time. The objective of this study is to describe and evaluate a compliance real-time monitoring system of the brace usage in AIS patients. Methods A compliance real-time monitoring system (specifically consisting of a compliance monitor, a WeChat Mini Program, a cloud-based storage system and a website backstage management system) was designed to manage the brace treatment. Thirty patients receiving brace treatment were enrolled. They were told to upload the data at least once a day. Clinicians downloaded the compliance data and communicated with the patients online based on their analysis of data at least once every 3 months. The measured force, quality compliance (measured force / baseline force), measured time, and quantity compliance (measured time/ prescribed time) were used to evaluate patient compliance. Patients were also asked to rate their satisfaction at the final follow-up. Results Twenty-eight patients were included in the final analysis. The mean baseline force was 1.23 ± 0.28 N. The mean measured force was 0.79 ± 0.29 N. The mean quality compliance was 64.8 ± 22.2%. The prescribed time of all patients was 23 h. The mean measured time was 14.1 ± 2.9 h. The mean quantity compliance was 61.3 ± 12.6%. Both the quality and quantity compliance during the first 3 months of treatment was significantly lower than the latter 3 months. In this study, 96.4% (27/28) patients were satisfied with the use of the monitoring system, among whom 21.4% (6/28) are very satisfied and 75.0% (21/28) are somewhat satisfied. Conclusions The compliance real-time monitoring system, without evaluating the clinical and radiographic outcomes for now, has already shown some feasibility and effectiveness for the management of the brace usage in AIS patients. This system, as a useful tool for online patient management and patient-clinician communication, would be potentially employed on a large scale in future for clinicians to improve the compliance and satisfaction of AIS patients who have received brace treatment.

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“…Lung cancer is the most common cause of cancer-related deaths worldwide. Despite advances over the past decade in new targeted therapies, diagnostics, staging, and surgical techniques, as well as new chemotherapy and radiation therapy, lung cancer mortality remains high (1). Lung cancer mainly includes non-small cell lung cancer, which includes squamous cell carcinoma, adenocarcinoma, and Abbreviations: IL-34, interleukin 34; LUAD, lung adenocarcinoma; TCGA, The Cancer Genome Atlas; OS, overall survival; TNM, tumor-node-metastasis; mRNA, messenger RNA; CSF, Colony-stimulating factor; IHC, immunohistochemistry; GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; GSEA, Gene Set Enrichment Analysis; ACT, Adjuvant chemoradiotherapy; NTU, Nantong University.…”

Section: Introductionmentioning

confidence: 99%

Loss of IL-34 Expression Indicates Poor Prognosis in Patients With Lung Adenocarcinoma

et al. 2021

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Interleukin 34 (IL-34), an additional ligand of the colony-stimulating factor-1 receptor (CSF-1R), promotes the secretion of pro-inflammatory cytokines and stimulates NF-κB and JNK-related signaling pathways. However, the potential mechanism and prognostic value of IL-34 in lung adenocarcinoma (LUAD) remain obscure. In this study, IL-34 was found to be downregulated in LUAD tissues compared with para-carcinoma tissues, and loss of IL-34 expression was correlated with shorter overall survival (OS), which was validated by bioinformatics\ analysis in TCGA (The Cancer Genome Atlas) cohort and immunohistochemical analysis in the NTU (Nantong University) cohort, respectively. Subsequently, loss of IL-34 promotes negative regulation of the immune system and inhibits the infiltration of immune cells. Moreover, IL-34 deficiency was shown to be an independent adverse prognostic factor for patients with LUAD, and subgroup analysis indicated that IL-34 might contribute to the stratified management of patients with LUAD. IL-34-based nomogram model significantly improved the accuracy of prognostic predictions for OS of patients with LUAD, both in the TCGA cohort and the NTU cohort. Taken together, our data suggested that loss of IL-34 expression is associated with poor prognosis and negative regulation of the immune system of patients with LUAD, contributing to the stratified management of patients with LUAD.

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Compliance with night-time overcorrection bracing in adolescent idiopathic scoliosis: Result from a cohort follow-up

Cited by 16 publications

References 24 publications

3D modeling of human spine and the cobb angle measurement in scoliosis patients

3D modeling of human spine and the cobb angle measurement in scoliosis patients

A compliance real-time monitoring system for the management of the brace usage in adolescent idiopathic scoliosis patients: a pilot study

Loss of IL-34 Expression Indicates Poor Prognosis in Patients With Lung Adenocarcinoma

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