Complications After Pancreatectomy for Neuroendocrine Tumors: A National Study

ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Neoplasms of the Digestive System: Well-Differentiated Pancreatic Non-Functioning Tumors

“…They differ according to the tumor site: lesions of the pancreatic head are treated with a pancreaticoduodenectomy (PD) while lesions of the body and tail with a left pancreatectomy (LP) with or without spleen preservation. Typical pancreatic resections are associated with a high incidence of perioperative complications [95] as well as exocrine and endocrine insufficiency. Atypical resections have been proposed in the management of NF pancreatic NETs, especially when well demarcated and small in size.…”

Behavior of small, asymptomatic, nonfunctioning pancreatic neuroendocrine tumors (NF-PNETs)

“…Some authors suggest that for NF-PNETs measuring 2 cm, a nonoperative management can be considered, and the risks and benefits of surgical resection should be carefully weighed in and an overall complication rate of 29.6% after pancreatectomy for PNETs. 20 The majority of complications involved postoperative infections (11.1%), digestive system complications (8.8%), or pulmonary compromise (7.3%). In-hospital mortality EUS-FNA ¼ endoscopic ultrasound-guided fine-needle aspiration; NET ¼ neuroendocrine tumor.…”

Conservative management and parenchyma-sparing resections of pancreatic neuroendocrine tumors: Literature review

“…The conservative 'wait and see' management and the parenchyma-sparing techniques, when indicated, can both reduce the risk of pancreas failure and the incidence of tumor recurrence/ malignant progression [7].…”