“…In the next example, in which this same woman must now undergo radiotherapy, a known factor predisposing her to failure, her risk of explantation almost doubles to 8.8%, a risk multiplier consistent with past reports. 52,53 When further comorbidities are added, the benefits of precision risk calculation become further evident. A BMI of 30 kg/m 2 and smoking status are added in addition to radiotherapy, causing her 1-year risk of explantation to rise to 26% and risk of any complication at all exceeds 40%, which may be sufficient reason for her to consider alternatives such as autologous reconstruction.…”