“…The mortality rate in the large US cohort (14%) was similar to that in our analysis [16]. Another recent large study ( n = 4838) by Ng et al.…”
Section: Discussionsupporting
confidence: 89%
“…1). One additional study is highlighted separately, because it was not eligible for inclusion in our data analysis, yet it possessed valuable information on the use and outcomes of TV-TP therapy in a very large US patient cohort ( n = 360,233) [16]. Fig.…”
Section: Resultsmentioning
confidence: 99%
“…In 2019, the largest study to date on the use of TV-TP therapy and outcomes related to it was published on a US patient cohort from the National Inpatient Sample (NIS) database [16]. It reviewed over 360,000 patient records between 2004 and 2014.…”
Section: Resultsmentioning
confidence: 99%
“…An analysis performed in the NIS database in the United States between 2003 and 2014 included 43,472 patients and showed an increasing trend in TV-TP-related periprocedural complications up to 17.7% in 2014 (Rozen et al., unpublished data). An even larger study reporting on outcomes of TV-TP in the United States included over 350,000 patients and used the same NIS database for the analysis [16]. Although only potential complications could have been identified, a lower rate of cardiac perforations was observed (0.6%) in this large cohort.…”
Section: Discussionmentioning
confidence: 99%
“…The total number of complications found by Metkus et al. was strikingly low at 3.9% [16]. However, there are some important limitations to consider: no data were available on the implant procedure, and complications with no available ICD codes could have been missed (e.g.…”
Transvenous temporary cardiac pacing therapy (TV-TP) is widely used to treat life-threatening arrhythmias. Yet aggregated evidence on TV-TP is limited. We conducted a systematic scoping review to evaluate indications, access routes and complications of TV-TP, as well as permanent pacemaker therapy (PPM) following TV-TP. Clinical studies concerning TV-TP were identified in Ovid MEDLINE. Case studies and studies lacking complication rates were excluded. To assess complication incidence over time, differences in mean complication rates between 10-year intervals since the introduction of TV-TP were evaluated. We identified 1398 studies, of which 32 were included, effectively including 4546 patients. Indications varied considerably; however TV-TP was most commonly performed in atrioventricular block (62.7%). The preferred site of access was the femoral vein (47.2%). The mean complication rate was 36.7%, of which 10.2% were considered serious. The incidence of complications decreased significantly between 10-year interval groups, but remained high in the most recent time period (22.9%) (analysis of variance; p < 0.001). PPM was required in 64.2% of cases following TV-TP. Atrioventricular block was the primary indication for TV-TP; however indications varied widely. The femoral vein was the most frequent approach. Complications are common in patients undergoing TV-TP. Although a decrease has been observed since its introduction, the clinical burden remains significant. The majority of patients who underwent TV-TP required PPM therapy.Electronic supplementary materialThe online version of this article (10.1007/s12471-019-01307-x) contains supplementary material, which is available to authorized users.
“…The mortality rate in the large US cohort (14%) was similar to that in our analysis [16]. Another recent large study ( n = 4838) by Ng et al.…”
Section: Discussionsupporting
confidence: 89%
“…1). One additional study is highlighted separately, because it was not eligible for inclusion in our data analysis, yet it possessed valuable information on the use and outcomes of TV-TP therapy in a very large US patient cohort ( n = 360,233) [16]. Fig.…”
Section: Resultsmentioning
confidence: 99%
“…In 2019, the largest study to date on the use of TV-TP therapy and outcomes related to it was published on a US patient cohort from the National Inpatient Sample (NIS) database [16]. It reviewed over 360,000 patient records between 2004 and 2014.…”
Section: Resultsmentioning
confidence: 99%
“…An analysis performed in the NIS database in the United States between 2003 and 2014 included 43,472 patients and showed an increasing trend in TV-TP-related periprocedural complications up to 17.7% in 2014 (Rozen et al., unpublished data). An even larger study reporting on outcomes of TV-TP in the United States included over 350,000 patients and used the same NIS database for the analysis [16]. Although only potential complications could have been identified, a lower rate of cardiac perforations was observed (0.6%) in this large cohort.…”
Section: Discussionmentioning
confidence: 99%
“…The total number of complications found by Metkus et al. was strikingly low at 3.9% [16]. However, there are some important limitations to consider: no data were available on the implant procedure, and complications with no available ICD codes could have been missed (e.g.…”
Transvenous temporary cardiac pacing therapy (TV-TP) is widely used to treat life-threatening arrhythmias. Yet aggregated evidence on TV-TP is limited. We conducted a systematic scoping review to evaluate indications, access routes and complications of TV-TP, as well as permanent pacemaker therapy (PPM) following TV-TP. Clinical studies concerning TV-TP were identified in Ovid MEDLINE. Case studies and studies lacking complication rates were excluded. To assess complication incidence over time, differences in mean complication rates between 10-year intervals since the introduction of TV-TP were evaluated. We identified 1398 studies, of which 32 were included, effectively including 4546 patients. Indications varied considerably; however TV-TP was most commonly performed in atrioventricular block (62.7%). The preferred site of access was the femoral vein (47.2%). The mean complication rate was 36.7%, of which 10.2% were considered serious. The incidence of complications decreased significantly between 10-year interval groups, but remained high in the most recent time period (22.9%) (analysis of variance; p < 0.001). PPM was required in 64.2% of cases following TV-TP. Atrioventricular block was the primary indication for TV-TP; however indications varied widely. The femoral vein was the most frequent approach. Complications are common in patients undergoing TV-TP. Although a decrease has been observed since its introduction, the clinical burden remains significant. The majority of patients who underwent TV-TP required PPM therapy.Electronic supplementary materialThe online version of this article (10.1007/s12471-019-01307-x) contains supplementary material, which is available to authorized users.
Objectives: This multicenter retrospective study of the initial U.S. experience evaluated the safety and efficacy of temporary cardiac pacing with the Tempo ® Temporary Pacing Lead.Background: Despite increasing use of temporary cardiac pacing with the rapid growth of structural heart procedures, temporary pacing leads have not significantly improved. The Tempo lead is a new temporary pacing lead with a soft tip intended to minimize the risk of perforation and a novel active fixation mechanism designed to enhance lead stability.Methods: Data from 269 consecutive structural heart procedures were collected.Outcomes included device safety (absence of clinically significant cardiac perforation, new pericardial effusion, or sustained ventricular arrhythmia) and efficacy (clinically acceptable pacing thresholds with successful pace capture throughout the index procedure). Postprocedure practices and sustained lead performance were also analyzed.Results: The Tempo lead was successfully positioned in the right ventricle and achieved pacing in 264 of 269 patients (98.1%). Two patients (0.8%) experienced loss of pace capture. Procedural mean pace capture threshold (PCT) was 0.7 ± 0.8 mA.There were no clinically significant perforations, pericardial effusions, or sustained device-related arrhythmias. The Tempo lead was left in place postprocedure in 189 patients (71.6%) for mean duration of 43.3 ± 0.7 hr (range 2.5-221.3 hr) with final PCT of 0.84 ± 1.04 mA (n = 80). Of these patients, 84.1% mobilized out of bed with no lead dislodgment.
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