Complications following percutaneous liver biopsy

Piccinino, F; Sagnelli, E.; Pasquale, Giuseppe; Giusti, G.; Battocchia, A; Bernardi, Massimo; Bertolazzi, R.; Bianchi, Francesco; Brunelli, E.; Budillon, G; Buscarini, L; Cargnel, Antonietta; Carrara, Greta; Carulli, Nicola; Caruso, Luigi; Cataldi, Valentina; Celle, G; Chiandussi, L; Chiesa, L.; Colombo, Massimo; Coltortí, M; Bac, Carlo De; Blanco, C. Del Vecchio; Marco, G. Di; Fiaccadori, Fabíola Souza; Filippazzo, M.G.; Fornari, Fabio; Francavilla, A.; Frezza, Michela; Gallo, V.; Galvani, V.; Givatto, T.; Iannuzzi, C; Izzo, Carmela; Moli, Salvatore Le; Longo, Giuseppe; Magnani, Giuseppe; Manaï, Mohamed; Manenti, F.; Manghisi, O. G.; Manzillo, G; Marenco, G.; Miglio, F; Molino, Gianpaolo; Mosca, Pierluigi; Moschetta, R.; Panella, C.; Panichi, G; Parrilli, G.; Pastore, Giuseppe; Peluso, Carla; Picciotto, Antonino; Pilleri, G; Pisi, E; Leòn, Maurizio Ponz de; Rago, M.; Raimondo, G.; Realdi, Giuseppe; Rizzetto, M.; Rizzo, Aroldo; Ronchi, G.; Fanelli, Fabrizio; Ruggiero, Giuseppe; Russo, Aniello; Satta, Andrea; Sansonno, Domenico; Struglia, C.; Tolentino, P.J.; Tremolada, F.; Trischitta, C.; Verme, G; Viganó, Paolo; Visco, G; Zivelonghi, P.

doi:10.1016/s0168-8278(86)80075-7

Cited by 1,044 publications

(159 citation statements)

References 22 publications

Supporting

Mentioning

152

Contrasting

Unclassified

Order By: Relevance

“…Other complications include hemobilia, organ injuries, arterio-venous fistula and septic shock [1,2,5]. Piccinino et al investigated 68,276 biopsies over 10 years and the major complications were found to be shock, pneumothorax, hemoperitoneum and biliary peritonitis [6]. Çolakoğlu et al evaluated 3,531 liver biopsies peformed between 1975 and 1993, and the biopsy-related major complications.…”

Section: Discussionmentioning

confidence: 99%

Complications and Efficiency of Liver Biopsies using the Tru-Cut Biopsy Gun

Çevik

Aykın

Naz

2009

J Infect Dev Ctries

View full text Add to dashboard Cite

Objectives: The study aimed to evaluate the complications and quality of the specimens of percutaneous liver biopsy in patients with chronic viral hepatitis who were scheduled for treatment and also to evaluate the contribution of the knowledge of ultrasound guided (USG) biopsy localization to the existing data. Methodology: Liver biopsies conducted at our clinic between 2003 and 2008 were retrospectively evaluated. In 53.8% of the cases, hepatobiliary USG was performed to mark the localization of the biopsy site. An automatically triggered Tru-Cut biopsy gun was used. Results: Biopsies waere taken from the livers of 236 patients (46.6% male, 53.4% female) with a mean age of 47.1 ± 12.5 years. The majority of patients had hepatitis C (61.9%); 1.6% experienced major complications (3 patient biliary peritonitis, 1 patient liver bleeding); 52.1% of the samples were ≥ 1 cm in length; And 69.7% of the biopsy samples with specified portal area had ≥ 4 portal areas. There was no statistically significant difference between the patients with localized and non-localized biopsy site in terms of major complications and length of biopsy samples ( respectively p = 1.000, p = 0.209 ). Conclusion: We believe that percutaneous liver biopsy using Tru-Cut biopsy gun can be peformed safely, with complications in 1.6% of the procedures. The length of the biopsy specimen is shorter than ideal values. Evaluation of the patients with and without USG-guided biopsy revealed no significant difference in terms of major complications and specimen size.

show abstract

Section: Discussionmentioning

confidence: 99%

Complications and Efficiency of Liver Biopsies using the Tru-Cut Biopsy Gun

Çevik

Aykın

Naz

2009

J Infect Dev Ctries

View full text Add to dashboard Cite

show abstract

“…As regards the needle to be used, studies so far suggest that the Menghini needle causes a lower number of complications [1, 8, 24]than the Tru-Cut needle [5, 6, 24, 25, 26, 27]. However, an analysis of the complications based on histology should be made, because it is likely that the Menghini needle has been used for less severe pathologies and, therefore, in patients at lower risk.…”

Section: Discussionmentioning

confidence: 99%

“…Other studies have reported complications within 3 h [1, 4, 5, 25]or 6 h [18], and a minimum postbiopsy period of observation of 3 h has thus been recommended for outpatient LB [5], as the complication reported after 6 h, without premonitory signs, can be considered an exception [1], in spite of the fact that delayed bleeding 3 days after LB has also been reported [4]. In the light of our experience, we believe that the minimum observation period can reasonably be reduced to 4 h in out-patient LB, bearing in mind that the more serious the complication is, the earlier it generally occurs.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Percutaneous Liver Biopsy: A Safe Outpatient Procedure?

et al. 2001

View full text Add to dashboard Cite

Following the discovery of hepatitis C virus, more liver biopsies (LB) than before are being performed to assess the severity of liver disease. In this study, following the recommendations for outpatient LB made by the Patient Care Committee of the American Gastroenterological Association, we assessed the feasibility and benefits of LB performed as an outpatient versus inpatient procedure over the last 7 years in our centre. The study included 1,581 patients consecutively examined in our institute; all LBs were performed by a single operator with a 16-gauge needle using the Menghini technique, and in all cases the puncture site was determined using prebiopsy ultrasound. Liver lesions were classified using grading and staging scores. Ultrasound-guided LB of focal lesions were excluded from this study. LB was performed on 1,318 outpatients and 263 hospitalized patients. The mean age of the hospitalized patients was higher than that of the outpatients (p < 0.0001). As major side effects, one death and one haemoperitoneum requiring blood transfusion were recorded in the hospitalized patients. As minor side effects, one haemorrhage occurred in the hospitalized patients, whereas a case of haemobilia and 2 cases of subcapsular haematoma were recorded in the outpatients. In both groups pain at the puncture site was the most frequent minor complication which easily resolved after non-steroid drug administration. Severe histological diagnoses, both in terms of grading and staging, were significantly associated with hospitalized patients. In conclusion, by carefully selecting patients and using prebiopsy ultrasound to assess the puncture site, outpatient LB can be safely performed in most cases; this procedure should be more widely used, because it has met with the favour of patients who are able to return home the same day and reduces public health care service costs.

show abstract

“…The complication rate in this study was 0.3%. Another retrospective study of 1000 biopsies showed a 5.9% complication rate with 5.3% of hospitalizations related to local pain or hypotension [10] [11].…”

Section: Introductionmentioning

confidence: 99%

Variables Associated with Cirrhosis Diagnosis in Patients with Chronic Hepatitis C: A Case-Control Study

Sousa¹,

Costa²,

Souza³

et al. 2015

Health

View full text Add to dashboard Cite

The diagnosis of liver cirrhosis in patients with chronic hepatitis C has not always been easy, since the gold standard method is the liver biopsy, which is an invasive procedure with interobserver accuracy problems and there have been reports of complications including records of deaths due to hemoperitoneum. Cirrhosis changes the prognosis of the subject with hepatitis C and requires a different clinical management. This study aimed to identify clinical and laboratory variables associated with the diagnosis of cirrhosis in the ultrasonography of patients infected with hepatitis C. In a case-control study, we evaluated 70 cirrhotic patients with chronic hepatitis C compared to a control group of 70 non-cirrhotic people with positive HCV. The results showed, through logistic regression analysis, that the variables blood donor and professional athlete, adjusted for alcohol consumption, showed OR 0.24 and 0.18, with p values of 0.044 and 0.035, respectively. We conclude that the diagnosis of cirrhosis in patients with chronic hepatitis C remains challenging, but the patients with the condition of blood donor or professional athlete prove to be less likely to cirrhosis in ultrasonography in the initial consultation.

show abstract

Complications following percutaneous liver biopsy

Cited by 1,044 publications

References 22 publications

Complications and Efficiency of Liver Biopsies using the Tru-Cut Biopsy Gun

Complications and Efficiency of Liver Biopsies using the Tru-Cut Biopsy Gun

Percutaneous Liver Biopsy: A Safe Outpatient Procedure?

Variables Associated with Cirrhosis Diagnosis in Patients with Chronic Hepatitis C: A Case-Control Study

Contact Info

Product

Resources

About