Complications Following Total Hip Arthroplasty

Rajpura, Asim; Board, Tim

doi:10.5772/53030

Cited by 3 publications

(2 citation statements)

References 221 publications

(230 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Also, a study discussing THA revision due to dislocation concluded that the posterior approach increased the risk of revision for dislocation by 1.7 times [6,9]. Correspondingly, a posterior approach has been shown to be a major risk factor for dislocation due to reduced cup anteversion, which may be related to surgeon expertise [13].…”

Section: Discussionmentioning

confidence: 99%

The Outcomes and Revision Rate of Total Hip Arthroplasty in a Single Tertiary Center: A Retrospective Study

Alsheikh¹,

Alhandi²,

Almutlaq³

et al. 2022

Cureus

View full text Add to dashboard Cite

IntroductionTotal hip arthroplasty (THA) is a commonly performed and successful orthopedic practice procedure. However, failure of arthroplasty may require revision THA and pose substantial clinical challenges for orthopedic surgeons. Therefore, this retrospective study aimed to estimate the revision rate of THA and its risk factors at a tertiary care hospital. MethodsA retrospective cohort study was conducted in 2021 of patients who had undergone THA during 2016-2020 in a tertiary care hospital. All patients above 18 years old who had a THA were included in the study. The data was collected from patients' medical charts/electronic databases. ResultsA total of 148 THAs were included in this study. In total, 77 (52%) were females, and 71 (48%) were males. The average age of our patients was 49±17 years old, and the mean recorded BMI was 29.6. A total of 62% (n=92/148) of our participants were shown to have at least one comorbid disease, with hypertension being the most common comorbidity. Our findings show that half of the patients, 74 (50%), had a THA due to both primary and secondary osteoarthritis, 37 (25%) patients had avascular necrosis of the hip, and 25 (17%) were due to trauma. The most performed surgical approach was Kocher-Langenbeck (posterior) approach on 128 (86%), followed by the Hardinge (lateral) approach on 20 (13.51%). The most observed complication in the patients was postoperative pain in 35 (23.65%), followed by UTIs in 5 (3.38%). Of the 148 patients, nine (6.08%) had revision surgery. Regarding the revision rate, male patients were associated with a significantly higher rate of revision (P=<0.001), and older patients had a significantly increased risk of revision (P=0.026). Patients who developed complications, such as UTI, were associated with a higher revision rate (P=0.035). Also, a posterior approach (Kocher-Langenbeck) of the procedure was significantly linked to an increased risk of revision (P=0.014). ConclusionAll in all, there are multiple associated factors with an increased incidence of revision THA. For example, male patients, older patients, complication development during the hospital stay, and posterior surgical approach were all associated with a significantly higher rate of revision.

show abstract

Section: Discussionmentioning

confidence: 99%

The Outcomes and Revision Rate of Total Hip Arthroplasty in a Single Tertiary Center: A Retrospective Study

Alsheikh¹,

Alhandi²,

Almutlaq³

et al. 2022

Cureus

View full text Add to dashboard Cite

show abstract

“…Furthermore, THA has been performed on a large number of patients worldwide. It is among the most frequently executed orthopaedic operations, and is an increasingly common and successful operation of the last decades [2][3][4]. Today the average lifetime of a hip prosthesis is approximately 15 years [5,6].…”

Section: Introductionmentioning

confidence: 99%

Biomechanical model based evaluation of Total Hip Arthroplasty therapy outcome

Eschweiler

Hawlitzky

Quack

et al. 2017

Journal of Orthopaedics

View full text Add to dashboard Cite

show abstract

Levels of Matrix Metalloproteinases in Arthroplasty Patients and Their Correlation With Inflammatory and Thrombotic Activation Processes

Alexander

Banos

Abro

et al. 2016

Clin Appl Thromb Hemost

View full text Add to dashboard Cite

An imbalance of matrix metalloproteinases (MMPs) and their inhibitors is thought to play a major role in the pathophysiology of joint diseases. The aim of this study is to provide additional insights into the relevance of MMP levels in arthroplasty patients in relation to inflammation and thrombosis. Deidentified plasma samples from 100 patients undergoing total hip arthroplasty or total knee arthroplasty were collected preoperatively, on postoperative day 1, and on postoperative day 3. Tissue inhibitor of MMP 4, tumor necrosis factor α (TNF-α), pro-MMP1, MMP3, MMP9, MMP13, and d-dimer were measured using enzyme-linked immunosorbent assay kits. A biochip array was used to profile interleukin (IL) 2, IL-4, IL-6, IL-8, IL-10, vascular endothelial growth factor (VEGF), interferon gamma, TNF-α, IL-1α, IL-1β, monocyte chemoattractant protein 1, and endothelial growth factor (EGF) levels. The levels of MMP1, MMP9, MMP13, and TNF-α were elevated preoperatively in arthroplasty patients when compared to healthy individuals. The concentrations of MMP1 and MMP9 increased slightly in postsurgical samples. d-Dimer levels were elevated preoperatively, increased postoperatively, and started decreasing on postoperative day 3. Significant correlations between MMP9 with TNF-α, IL-6, IL-8, VEGF, and EGF were identified. Elevated preoperative MMP1, MMP9, and MMP13 concentrations suggest that they may play a role in the pathogenesis of arthritis. There is also evidence of increased coagulation activity and possible upregulation of several MMPs postsurgically. Correlation analysis indicates that MMP9 levels may potentially be related to inflammation and thrombosis in arthroplasty patients.

show abstract

Complications Following Total Hip Arthroplasty

Cited by 3 publications

References 221 publications

The Outcomes and Revision Rate of Total Hip Arthroplasty in a Single Tertiary Center: A Retrospective Study

The Outcomes and Revision Rate of Total Hip Arthroplasty in a Single Tertiary Center: A Retrospective Study

Biomechanical model based evaluation of Total Hip Arthroplasty therapy outcome

Levels of Matrix Metalloproteinases in Arthroplasty Patients and Their Correlation With Inflammatory and Thrombotic Activation Processes

Contact Info

Product

Resources

About