1999
DOI: 10.1002/(sici)1097-0347(199901)21:1<12::aid-hed2>3.0.co;2-#
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Complications of anterior craniofacial resection

Abstract: Background The complications associated with anterior craniofacial resections for benign and malignant tumors were reviewed in 104 patients treated between January 1981 and June 1996. Methods Information regarding patient characteristics, histologic type, history of prior therapy, extent of the disease, extent of surgical procedure, and type of reconstruction were entered in a microcomputer database. To better understand and stage postoperative complications, we divided them into early (<14 days) and late (>14… Show more

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Cited by 100 publications
(108 citation statements)
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References 24 publications
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“…Mortality rates for surgical series that have included similar tumors to our series are generally 2.1% to 8.0%, 1,3,15,17,19 whereas complication rates have been reported to be 33% to 64%. 3,5,15,17,23 Previous therapies, particularly combinations of surgery, chemotherapy, and radiation therapy, are known risk factors for increased complications after anterolateral skull base surgery. 15,16 Series that have examined mostly anterior craniofacial procedures report CSF leaks and infections as being the most common surgical complications, whereas series reporting mainly lateral skull base surgeries report relatively more cerebrovascular and cranial nerve complications.…”
Section: Discussionmentioning
confidence: 99%
“…Mortality rates for surgical series that have included similar tumors to our series are generally 2.1% to 8.0%, 1,3,15,17,19 whereas complication rates have been reported to be 33% to 64%. 3,5,15,17,23 Previous therapies, particularly combinations of surgery, chemotherapy, and radiation therapy, are known risk factors for increased complications after anterolateral skull base surgery. 15,16 Series that have examined mostly anterior craniofacial procedures report CSF leaks and infections as being the most common surgical complications, whereas series reporting mainly lateral skull base surgeries report relatively more cerebrovascular and cranial nerve complications.…”
Section: Discussionmentioning
confidence: 99%
“…An overall complication rate of 33% was observed, with other studies reporting surgical complication rates of 52%, highlighting the clinical challenge presented by these malignancies (4,11). Wound complications were associated with prior radiotherapy and medical comorbidities (9).…”
mentioning
confidence: 82%
“…This surgical paradigm has stood for Ͼ 60 years, with incremental refinements incorporated along the way, including advances in imaging techniques, the development of microvascular and skull base approaches, and the formation of multidisciplinary teams (1,3,4,9,10,16,19,23).…”
mentioning
confidence: 99%
“…b Facial translocation approach-post operative appearance and improvement in microvascular technique, results have steadily improved. [36][37][38][39][40][41][42][43][44][45][46][47][48][49] Peter Neligen et al in 199643, described single institute experience of skull base reconstruction in 90 patients using local, regional or free flap. Overall complication rate in local flap and free flap group was approximately similar (38.8% vs 33.5%).…”
Section: Reconstruction Of Skull Base Defectsmentioning
confidence: 99%