2018
DOI: 10.1038/s41395-018-0115-7
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Complications of Antireflux Surgery

Abstract: Antireflux surgery anatomically restores the antireflux barrier and is a therapeutic option for proton pump inhibitor (PPI)-refractory gastroesophageal reflux disease or PPI intolerance. Laparoscopic fundoplication is the standard antireflux surgery, though its popularity has declined due to concerns regarding wrap durability and adverse events. As the esophagogastric junction is an anatomically complex and dynamic area subject to mechanical stress, wraps are susceptible to disruption, herniation or slippage. … Show more

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Cited by 103 publications
(83 citation statements)
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“…Similar to existing anti-reflux surgery, the procedure as such can have complications of importance that require special care: bleeding and infection [28]. Infection could be a serious issue when placing an implant, however, the consequences of an infection are reduced if the device is completely covered/invaginated in the stomach wall by stomach-to-stomach sutures, thereby avoiding that the infection is spread to the device.…”
Section: Discussionmentioning
confidence: 99%
“…Similar to existing anti-reflux surgery, the procedure as such can have complications of importance that require special care: bleeding and infection [28]. Infection could be a serious issue when placing an implant, however, the consequences of an infection are reduced if the device is completely covered/invaginated in the stomach wall by stomach-to-stomach sutures, thereby avoiding that the infection is spread to the device.…”
Section: Discussionmentioning
confidence: 99%
“…Dysphagia and gas-bloat syndrome can be side effects associated with GERD surgery. 41 The long-term use of PPI was associated with various diseases, such as osteoporosis, dementia, infections, and cardiovascular disease. 10 However, these issues could not be addressed in this study, because evidence of their impact on costs and clinical outcomes has been unknown.…”
Section: Discussionmentioning
confidence: 99%
“…Similar to existing anti-re ux surgery, the procedure as such can have complications of importance that require special care: bleeding and infection [28]. Infection could be a serious issue when placing an implant, however, the consequences of an infection are reduced if the device is completely covered/invaginated in the stomach wall by stomach-to-stomach sutures, thereby avoiding that the infection is spread to the device.…”
Section: Summary Of the Main E Cacy Endpointmentioning
confidence: 99%