Complications of cutaneous surgery in patients taking clopidogrel-containing anticoagulation

The safety of Mohs surgery: A prospective multicenter cohort study

“…[2][3][4][5] Complications associated with Mohs surgery have been evaluated by prospective single-surgeon studies, as well as by retrospective multiple-surgeon studies. [6][7][8][9] Multicenter, prospective studies afford a higher level of clinical evidence and help to establish the safety profile of Mohs surgery in the ambulatory setting.…”

Complications With New Oral Anticoagulants Dabigatran and Rivaroxaban in Cutaneous Surgery

“…1 Although data suggest that patients taking aspirin, warfarin, or clopidogrel may be at slightly higher risk of minor bleeding from cutaneous surgery, these agents have not been associated with severe life-threatening hemorrhagic complications after cutaneous surgery. 2,3 In contrast, perioperative discontinuation of medically necessary aspirin and warfarin during cutaneous surgery has been associated with severe thrombotic complications (e.g., cerebrovascular accidents, transient ischemic attacks, myocardial infarctions, deep venous thromboses [DVT], pulmonary embolism [PE], retinal artery occlusion leading to blindness, and death). 4,5 The morbidity and magnitude of the potential hemorrhagic complications pale in comparison with these potential thrombotic events.…”

Hemothorax after chest tube insertion for pneumothorax as a complication of clopidogrel

“…Continuing anti-platelet agents may increase procedurerelated bleeding complications [3][4][5]. In emergency situations, some interventional procedures have to take place under or shortly after the cessation of antiplatelet treatment, despite the increased bleeding risk.…”

“…Not many data are available on the bleeding complication risks in patients receiving anti-platelet agents at the time of some procedures [3][4][5]. As the cause of hemothorax, clopidogrel has been reported in 3 cases [10][11][12].…”

“…Clopidogrel, along with aspirin, is recommended in the American College of Cardiology/American Heart Association guideline [2] and, therefore, an increasing number of patients suffering from cardiovascular diseases are treated with them. Clopidogrel treatment at the time of certain procedures increases the risk of significant bleeding complications [3][4][5]. Although very rare, emergency surgical procedures may be necessary for patients taking anti-platelet agents.…”