“…Incidence of moderate pulmonary hemorrhage, and hemothorax (CTCAE > 1) are higher in PC than heat-based modalities (eg. RFA, microwave: 0-3% [4,27]), originating from the thawing cycle may induce more fluid and bleeding. In addition to hyperemic change in the periphery of ablation zone, larger vessels remained in the central region in acute phase of PC also contributes the higher rate of hemorrhage [19].…”