When designing engine safety and compliance with airworthiness regulations, it is important to determine the variation of rotor rotational speed and other parameters of aero-engine under shaft failure scenarios. In this paper, a transient process simulation model is established using the component method for a high bypass ratio two-shaft direct-drive turbofan engine. It helps analyze the response of engine rotor speed and key temperature parameters after the failure of the low-pressure shaft, the influence of the fuel supply, low-pressure turbine efficiency, and rotor resistance torque on the response of the parameters. The results demonstrate that the sudden increase of the low-pressure shaft speed at the turbine end after the failure of the low-pressure shaft is the most important factor affecting the engine safety design. The fuel supply, LPT efficiency, and resistance torque have significant effects on this sudden increase in speed.