The plant diversity has been and is the main theme of very diverse and different projects due to the need to know and use plant resources in a sustainable way; several factors have been identified that threaten this diversity, such as: the destruction of habitats, environmental pollution, overexploitation of resources, the introduction of exotic species and climate change. Although many and very diverse studies have been carried out on the diversity and vegetation of the country, the biodiversity of many regions and of various groups of plants is still unknown; as are the phanerogams of Oaxaca, which constitute 89.4% of the 255 families reported for the country (Espejo-Serna et al., 2004;Villaseñor, 2004). The 1841 genera represent 69% of the 2677 ocurrung in Mexico and the 8228 species in the state represent 37.3% of the 22397 in the country (Villaseñor, 2004), which shows the great diversity present in the state of Oaxaca. García-Mendoza ( 2004) reported for the state 223 families, 1712 genera and 7804 species of phanerogams, being the angiosperms, the best represented with 217 families, 1700 genera and 7752 species. In an update of these data, García-Mendoza & Meave (2011) reported 228 families, 1841 genera and 8228 species, of which 667 are endemic to Oaxaca. In Villaseñor (2016), 226 families, 1783 genera and 9411 species were reported. The importance of documenting the plant richness in many places is, therefore, cannot be postponed, if we also consider the accelerated destruction of ecosystems and the incomplete knowledge of their components. That is why the objective of this work was to develop an inventory of the phanerogamic flora of the municipality of San Juan Colorado, district of Jamiltepec, located in the south-western part of the state of Oaxaca.Between 2014 and 2017, several botanical collection trips were made to various locations in the municipality, giving preference to the best-preserved areas.Likewise, the specimens deposited in the ENCB, MEXU and UAMIZ herbaria were reviewed to detect the material from the study area. To identify or collate the determination of the specimens, specialized literature was used in each of the study groups. The supporting material collected during the study was deposited in the Herbario Metropolitano (UAMIZ) and duplicates were distributed to institutions in the pedicelo, sobrepuesto, con 2 lóculos, polen con dos alas prominentes como sacos en cada grano; megastrobilos (conillos) en grupos pequeños en el ápice de las ramas, escamas ovulíferas numerosas, leñosas, abiertas en corto período para recibir el polen y cerradas inmediatamente después de la polinización; óvulos 2 por escama. Fruto un cono, simétrico u oblicuo, con numerosas escamas abiertas o cerradas, el umbo dorsal o terminal a la escama variable en grosor, con una cúspide que termina en una espina aguda o gancho, persistente o decidua; semillas similares a nueces, aladas o sin ala, testa suave o endurecida.Género con cerca de 94 especies, para México se han citado 47 especies,