Composite Materials Based on (Cymene)Ru(II) Curcumin Additives Loaded on Porous Carbon Adsorbents from Agricultural Residues Display Efficient Antibacterial Activity

Abstract

Alternative composite materials with antibacterial activity have been developed by combining the porosity of carbon materials and the antibacterial activity of half sandwich (cymene)­Ru-curcumin complexes. Different types of activated carbon were used, from commercial to synthetic and also ones derived from agricultural waste residues (almond shells), to study the influence of their physicochemical properties. Half sandwich (cymene)­Ru­(II) curcumin complexes were selected on the basis of solubility and toxicity. The stability of the Ru complexes on carbon surfaces was analyzed by different techniques. The combination of low soluble Ru complexes with high porous carbon materials prevents leaching into solution and leads to new composite materials with high porosity, high adsorption capacity, and efficient antibacterial activity. All composite materials are able to maintain their surface free of Gram-negative bacteria even after 3 days in contact with a highly concentrated bacteria cultivation media. These features can be relevant to the use of such carbon composites in air filters or aqueous treatment applications.

Comparative study of binding interactions between three organometallic rhodium(III) complexes with curcuminoid ligands and human serum albumin

“…18 Caruso and Pettinari investigated the enhanced antitumor and antibacterial activities of arene-ruthenium(II) curcuminoid complexes. 19,20 Enyedy's group comparably studied the structures and the antiproliferative activities of half-sandwich ruthenium and rhodium complexes bearing curcumin and acetylacetone. 21 Su and co-workers reported the in vitro biological activities of half-sandwich ruthenium(II), rhodium(III), and iridium (III) complexes with curcuminoid ligands.…”

Antibacterial activity of copper pyrazolate coordination polymers

“…The Eppendorf tubes were subsequently shaken for 24 h at a speed of 160 rpm. Periodic withdrawals of 10 mL were made at 0, 2,4,6,8,10,12,14,16,18,20, and 24 h. To obtain the bacterial colony count, the supernatant fraction was diluted and included uniformly into Petri dishes containing the Plate Count Agar medium (OXOID PCA). Adopting the same procedure, bacterial strains untreated with 1-8 were used as a control (blank).…”

“…In recent years, we have focused our attention on composite materials with antimicrobial properties, obtained by anchoring or incorporating molecular complexes, CPs or MOFs in different matrices, such as cellulose, 19 carbon, 20 or plastics. [21][22][23] Many other matrices intended for different applications are reported in the literature.…”

Tethering (Arene)Ru(II) Acylpyrazolones Decorated with Long Aliphatic Chains to Polystyrene Surfaces Provides Potent Antibacterial Plastics

“…Our interests are devoted to the development of sustainable methodologies that afford scalable functional materials endowed with antimicrobial activity [23][24][25]. We have recently reported the preparation of composite materials formed by loading (cymene)Ru(II) curcumin complexes, previously reported to be potent antitumor agents [26], on porous carbon adsorbents, which display efficient antibacterial activity [27]. These features are relevant to the use of such carbon composites in air filters for some specific applications in the food and pharmaceutical industries, such as in air conditioning equipment, especially for hospitals, in operating rooms, [28] etc.…”