When designing blast-resistant reinforced concrete (RC) structures, reducing spall damage due to reflected tensile stress waves is a major problem. Furthermore, for rapid construction of the blast-resistant structures against sudden terrorist bomb attacks, it is necessary to build it with precast concrete walls and reduce the weight of the precast elements by reducing their size for ease of transportation and construction. In this study, to propose an idea for rapid construction and better blast resistance of blast-resistant RC structures, double-layered RC slabs composed of precast thin plates, 50 mm thick, were fabricated and utilized for contact detonation tests. The tests were conducted under a condition that the amount of explosives and the dimensions of specimen were constant respectively, and two types of concrete, normal concrete and polyethylene fiber reinforced concrete (PEFRC), were employed as the slab materials. Our results showed that creating an air cavity between the two layers of PEFRC slab was effective in reducing spall damage, while the air space had no advantage in normal RC, under a condition that the thickness of the air space was fixed at 15 mm. Furthermore, the above difference between PEFRC and normal RC slabs was discussed, based on the numerical result on the fracture process of the air-sandwiched normal RC slab.