Composition and global distribution of the mosquito virome - A comprehensive database of insect-specific viruses

Arbovirus surveillance in mosquitoes: Historical methods, emerging technologies, and challenges ahead

“…Among arthropods, mosquitoassociated viruses are the most extensively studied group, with the majority of novel viral species found in mosquitoes belonging to the Aedes, Anopheles, Culex, and Mansonia, and are insect-specific, that is, they do not have vertebrate hosts, such as arboviruses. 101,102 In addition to the discovery and characterization of arboviruses, the study of insect-specific viruses (ISVs), including virome studies and their interactions with invertebrate hosts, is a growing area of interest. Although there is still much to learn about these viruses and their relationship with arboviruses, mounting evidence suggests that ISVs can modulate their transmission capacity.…”

“…Among arthropods, mosquito-associated viruses are the most extensively studied group, with the majority of novel viral species found in mosquitoes belonging to the Aedes , Anopheles , Culex , and Mansonia , and are insect-specific, that is, they do not have vertebrate hosts, such as arboviruses. 101,102…”

“…Specifically, regarding the study of viral communities and viromes in mosquitoes, Brazil, the United States, China, and Australia have the highest number of articles. 102 However, more extensive sequencing of diverse mosquitoes in diverse habitats, as well as the mining of public sequence read databases, have the potential to discover and characterize novel arboviruses.…”

“…According to Moonen et al ., 102 mosquito virome studies have witnessed a significant increase in frequency over the last two decades. The number of such studies has increased from just two between 2000 and 2008 to an impressive 27 studies in recent years.…”

“…In contrast, sylvatic mosquitoes, such as Haemagogus , Sabethes , and Psorophora , have only a single record published for the same period. 102 Due to the importance of changes in land use, particularly deforestation, in promoting pathogen emergence and spillover events, 107,108 we believe that it is necessary to characterize the viromes in sylvatic mosquitoes to improve outbreak preparedness.…”