Composition of phenolic compounds and antioxidant attributes of Cyclea gracillima Diels extracts

Lin, Jer‐An; Liu, Shih Chuan; Kuo, Li Chun; Yang, Deng Jye

doi:10.1016/j.jfda.2017.03.004

Cited by 4 publications

(3 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A search of the literature did not reveal any information about the hydrogen peroxide scavenging capacity of HRLs of P. sidoides. According to previous results, Izuegbuna et al 44 showed the scavenging ability of P. inquinans leaves was high and dose-dependent, which could be a result of high levels of phenolic compounds and avonoids with high amounts of polyphenol, and antioxidant activities 45 . The overall results…”

Section: Discussionmentioning

confidence: 90%

Interval harvests changes phytochemical traits and biological activities of elite transformed hairy root cultures of African geranium (Pelargonium sidoides DC.)

Yousefian

Hamidoghli

Golkar

et al. 2022

Preprint

View full text Add to dashboard Cite

Tuberous roots of African geranium (Pelargonium sidoides DC.) with modern ethanolic formulation called EPs 7630 (Umckaloabo) have widely used in medicinal industries. The present study was aimed to explore changes in the phytochemical traits (i.e., phenolics, flavonoids, coumarins and hydroxycinnamic acid derivatives), protein content, enzymatic-antioxidants and antimicrobial activities of several high-yielding hairy root lines (HRLs) of P. sidoides harvested at different times. Among all HRLs, antioxidative responses (e.g., phenylalanine ammonia lyase, polyphenol oxidase and catalase contents) were increased in HRL10 exposed to higher interval harvests. Moreover, HRL10 exhibited a promising antimicrobial effect against Escherichia coli, with MIC equal to (2.61 mg/ml). In total 10 phytochemical compounds were identified through chromatographic (HPLC) technique including: umckalin (Um), gallic acid (GA), quercetin (QE), luteolin (LU) and the others. The extraction of HRs had high content of Um at 21 days (0.35 𝜇g/ml). The maximal phenolic yield in particular GA was enhanced to (5194.5 𝜇g/ml), about 10-fold in comparison with non-transformed roots (516 𝜇g/ml) on the 35th day. HRs were able to produce the maximum improvement in flavonoid glycosides (13.96 𝜇g QE/ml and 23.75 𝜇g LU/ml) at the end of culture period. The most profitable transgenic lines offers an interesting option to enhance the productivity. These results support the in vitro cultivation of HRs for supply as a natural product to prevent inflammation and microbial related disorders.

show abstract

Section: Discussionmentioning

confidence: 90%

Interval harvests changes phytochemical traits and biological activities of elite transformed hairy root cultures of African geranium (Pelargonium sidoides DC.)

Yousefian

Hamidoghli

Golkar

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…The conjugated aromatic ring structure, as well as hydroxyl and carbonyl groups in the phenolic compound, are reported to bind effectively to the metals, thereby inactivating ions through chelation. This is the widely accepted mechanism exhibited by phenolic compounds during free radicals and Reactive Oxygen Species quenching mechanism 18 . Hence, the estimated total phenolic content of S. androgynous contributes significantly towards its anti-oxidant potential Table 2.…”

Section: Discussionmentioning

confidence: 93%

Untitled

2021

IJPSR

View full text Add to dashboard Cite

Nanoparticles are being constantly exploited by the scientific community due to their versatile properties and applications. However, the synthesis of metallic nanoparticles achieved through conventional physical and chemical techniques is quite expensive and a labor-intensive process with serious consequences like instability of nanoparticles and toxic byproducts. Hence, green synthesis utilizing biological systems, including plants, bacteria, yeast, fungi, and algae proves to be a cost-effective and eco-friendly alternative. Plant extracts are a rich source of many bioactive compounds like secondary metabolites and often act as reducing and capping agents in the synthesis of nanoparticles. The present work deals with the synthesis of silver nanoparticles using aqueous leaf extract of Sauropus androgynous. Prior to the synthesis, phytochemical analysis and antioxidant potential were evaluated. Physical parameters, including silver metal ion concentration and the temperature were optimized for the effective synthesis of silver nanoparticles. The synthesized nanoparticles were characterized via UV-Visible spectroscopy, Fourier transform infrared spectroscopy (FTIR), Scanning Electron Microscopy (SEM), and X-ray crystallography (XRD). Finally, silver nanoparticles were evaluated for their antibacterial and anti-helminthic activity. Green synthesis of silver nano particles using S. androgynous was optimized at a conc. of 1mM of silver nitrate at a temperature of 70ºC. The characterization of silver nanoparticles revealed a spherical crystallite nature with particle sizes ranging from 16 nm -55nm. The nanoparticles exhibited antibacterial and anti-helminthic activity too. Hence, the green synthesized silver nanoparticle could be considered as a promising therapeutic choice against infectious pathological conditions.

show abstract

“…This could be as a result of high levels of phenolic compounds and flavonoids; compounds with high amounts of polyphenol have good antioxidant activities. 55 Thus the high antioxidant activity in the different extracts of Pelargonium inquinans could be as a result of the high amount of phenolic compounds and flavonoids.…”

Section: Hydrogen Peroxide Scavenging Activitymentioning

confidence: 99%

Estimation of Phytochemical, Vitamins Composition and Antioxidant Activity of Pelargonium inquinans Leaves

Izuegbuna¹,

Otunola²,

Bradley³

2019

View full text Add to dashboard Cite

Aims: To estimate the phytochemical and vitamins composition and the antioxidant activity of Pelargonium inquinans leaves. Background: Some plants that are used in the traditional setting for the management of different ailments have documented observations and scientific studies. However many other plants lack scientific reports to support their medicinal use. One of such plant is Pelargonium inquinans Ait that is traditionally used to treat headaches and flu by tribes in South Africa. Not much is known about its chemical composition. Methods: The phytochemical composition of acetone, aqueous and ethanol extract of leaves of Pelargonium inquinans as well as the vitamins A, C and E of its dried weight leaves and the antioxidant activities were evaluated using standard in vitro methods. The phytochemical composition and vitamins were determined spectrophotometrically, while the antioxidant activities were determined by DPPH, nitric oxide and hydrogen peroxide scavenging activity and phosphomolybdenum (total) antioxidant activity. Statistical analysis: The One-way analysis of variance (ANOVA) and the Tukey test were used to determine the differences among the means of the various samples. Results: The phytochemical composition differ significantly in the various extracts. The total phenolics were higher than other phytochemicals in all the extracts used. The hydrogen peroxide and DPPH scavenging activity were very high and dose-dependent. The aqueous extract had the highest antioxidant activity at 98.4 % of control (Hydrogen peroxide), while the ethanol extract had the lowest at 37.5% control (Nitric oxide). Conclusion: The results supports the notion that the Geraniaceae family and Pelargonium inquinans in particular is rich in polyphenolic compounds and has good antioxidant activity.

show abstract

Composition of phenolic compounds and antioxidant attributes of Cyclea gracillima Diels extracts

Cited by 4 publications

References 29 publications

Interval harvests changes phytochemical traits and biological activities of elite transformed hairy root cultures of African geranium (Pelargonium sidoides DC.)

Interval harvests changes phytochemical traits and biological activities of elite transformed hairy root cultures of African geranium (Pelargonium sidoides DC.)

Untitled

Estimation of Phytochemical, Vitamins Composition and Antioxidant Activity of Pelargonium inquinans Leaves

Contact Info

Product

Resources

About