Composition’s effect of Origanum Syriacum essential oils in the antimicrobial activities for the treatment of denture stomatitis

Abstract

This research has several purposes: First to assess the bacterial and fungal minimum inhibitory concentration of Origanum Syriacum essential oil. Second to quantify its bactericidal and fungicidal minimal concentration against S. aureus , S. mutans , and C. albicans found in denture stomatitis. The third purpose is to look at the influence of three different soils (Annaya, Bhanin and Michrif) on the essential oils composition. Three essential oils were extracted by hydro-distillation from three different Origanum Syriacum plant origins. Bioassays were conducted using a broth microdilution methods. Gas Chromatography analysis was used to calculate the abundance of most components in each essential oil. Post hoc tests assessed antimicrobial effects between ecotypes while Pearson’s test correlated the different components and their antimicrobial efficiency (α < 0.05). All tested essential oils were efficient against all microorganisms. Origanum Syriacum essential oils derived from Annaya and Bhanin soils showed a superior antimicrobial activity compared to the Michrif one. The most abundant component and most efficient among all essential oils constituents was carvacrol. It can be concluded that Origanum Syriacum essential oils have an antimicrobial activity, which depends on the ecotype, its origin and its composition. They might be used to start a clinical trial for the treatment of denture stomatitis.

Lemongrass oil disrupts the biofilm of Candida albicans MTCC 1637T on soft denture reliners at lower concentrations compared to thyme and tea tree oils

“…Due to the proportion of chemical constituents found in the synthesis of all three essential oils, the disparity in MIC and MFC values can be attributable. The difference between this study's findings and other studies can be mainly due to the variations in the composition of each plant ecotype and the difference in the study design [23].…”

“…Nonetheless, Shore A hardness value for the 28-day elevated value unquestionably correlated with the 24-hour Shore A hardness value for all the groups of essential oil, and this result is in agreement with studies conducted by Kim et al, [19]. In a study by Kim et al [19], "GC Reline Soft showed the mean durometer Shore A hardness of 50.13 ± 0.48 for 24 hours and 57.20 ± 0.28 for 28 days [23]." In the present study, there is a linear increase in mean hardness values in all groups from baseline, which are all significant (Fig.…”

Antifungal Action of Thyme and Basil Extracts on Different Denture Base Materials

“…Shamseddine and Chidiac (24) found that Origanum Syriacum have different antimicrobial efficiency against most strains related to DS with a higher efficiency associated to carvacrol content. Carvacrol is possibly one of the major components linked to Origanum Syriacum's anti-fungal effectiveness.…”

Prospects for using Origanum Syriacum (L.) as a source of antimicrobial agents

“…[ 8 9 ] Recent studies have also proven its antioxidant effect, anticancer, antibacterial, antifungal, and anti-acetylcholine oxidant. [ 3 10 11 12 13 14 15 16 17 18 ] Efficacy against colon cancer and breast cancer was also confirmed. [ 19 ] These medicinal properties are because of its richness in carvacrol (it can be up to79.8% from the content of essential oils) and Thymol (it can be up to 83, 8%).…”