Compositional characterization study on high -molecular -mass polymeric polyphenols in red wines by chemical degradation

Suo, Hao; Tian, Ruochen; Li, Jing; Zhang, Shuting; Cui, Yan; Li, Lingxi; Sun, Baoshan

doi:10.1016/j.foodres.2019.04.056

Cited by 33 publications

(47 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A broad oligomeric PAC peak was detected by the CAD detector (similar to the peak between 33-43 min in Figure 4), and further analysis revealed this peak represents polymerized tannins with six or more monomeric catechin units [51]. A number of other studies have reported similar chromatograms in approaches to characterize PAC-rich GS extracts [52][53][54]. However, many of these chromatograms do not report a second broad PAC peak similar to the peak observed between 60-68 min (Figure 4) in this study.…”

Section: Discussionmentioning

confidence: 60%

Optimization of the Extraction of Proanthocyanidins from Grape Seeds Using Ultrasonication-Assisted Aqueous Ethanol and Evaluation of Anti-Steatosis Activity In Vitro

Thilakarathna

Rupasinghe

2022

Molecules

View full text Add to dashboard Cite

Conventional extraction methods of proanthocyanidins (PAC) are based on toxic organic solvents, which can raise concerns about the use of extracts in supplemented food and nutraceuticals. Thus, a PAC extraction method was developed for grape seeds (GS) and grape seed powder using food-grade ethanol by optimizing the extraction conditions to generate the maximum yield of PAC. Extraction parameters, % ethanol, solvent: solid (s:s) ratio, sonication time, and temperature were optimized by the central composite design of the response surface method. The yields of PAC under different extraction conditions were quantified by the methylcellulose precipitable tannin assay. The final optimum conditions were 47% ethanol, 10:1 s:s ratio (v:w), 53 min sonication time, and 60 °C extraction temperature. High-performance liquid chromatography analysis revealed the presence of catechin, procyanidin B2, oligomeric and polymeric PAC in the grape seed-proanthocyanidin extracts (GS-PAC). GS-PAC significantly reduced reactive oxygen species and lipid accumulation in the palmitic-acid-induced mouse hepatocytes (AML12) model of steatosis. About 50% of the PAC of the GS was found to be retained in the by-product of wine fermentation. Therefore, the developed ethanol-based extraction method is suitable to produce PAC-rich functional ingredients from grape by-products to be used in supplemented food and nutraceuticals.

show abstract

Section: Discussionmentioning

confidence: 60%

Optimization of the Extraction of Proanthocyanidins from Grape Seeds Using Ultrasonication-Assisted Aqueous Ethanol and Evaluation of Anti-Steatosis Activity In Vitro

Thilakarathna

Rupasinghe

2022

Molecules

View full text Add to dashboard Cite

show abstract

“…Red wine contains high concentrations of polyphenolic compounds such as flavonoids (catechin, epicatechin, quercetin, anthocyanins, and procyanidins), resveratrol (3,5,4′-trihydroxystilbene), and polymeric tannins [15]. In general, red wine is rich in polyphenols and may be considered as an important polyphenols source in the diet [16].…”

Section: Bioactive Components In Red Winementioning

confidence: 99%

Red Wine Consumption and Cardiovascular Health

et al. 2019

View full text Add to dashboard Cite

Wine is a popular alcoholic beverage that has been consumed for hundreds of years. Benefits from moderate alcohol consumption have been widely supported by the scientific literature and, in this line, red wine intake has been related to a lesser risk for coronary heart disease (CHD). Experimental studies and meta-analyses have mainly attributed this outcome to the presence in red wine of a great variety of polyphenolic compounds such as resveratrol, catechin, epicatechin, quercetin, and anthocyanin. Resveratrol is considered the most effective wine compound with respect to the prevention of CHD because of its antioxidant properties. The mechanisms responsible for its putative cardioprotective effects would include changes in lipid profiles, reduction of insulin resistance, and decrease in oxidative stress of low-density lipoprotein cholesterol (LDL-C). The aim of this review is to summarize the accumulated evidence correlating moderate red wine consumption with prevention of CHD by focusing on the different mechanisms underlying this relationship. Furthermore, the chemistry of wine as well as chemical factors that influence the composition of the bioactive components of red wine are also discussed.

show abstract

“…High performance liquid chromatography (HPLC) and Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) can provide accurate molecular mass and structural information due to their high sensitivity, resolution, and rapid scanning speed. 19 In this study, the efficient extraction of ginsenoside at room temperature was reported for the rst time. The extraction conditions were optimized using response surface methodology (RSM).…”

Section: Introductionmentioning

confidence: 90%

Optimization of flash extraction, separation of ginsenosides, identification by HPLC-FT-ICR-MS and determination of rare ginsenosides in mountain cultivated ginseng

Shi

et al. 2020

RSC Adv.

Self Cite

View full text Add to dashboard Cite

show abstract

Compositional characterization study on high -molecular -mass polymeric polyphenols in red wines by chemical degradation

Cited by 33 publications

References 39 publications

Optimization of the Extraction of Proanthocyanidins from Grape Seeds Using Ultrasonication-Assisted Aqueous Ethanol and Evaluation of Anti-Steatosis Activity In Vitro

Optimization of the Extraction of Proanthocyanidins from Grape Seeds Using Ultrasonication-Assisted Aqueous Ethanol and Evaluation of Anti-Steatosis Activity In Vitro

Red Wine Consumption and Cardiovascular Health

Optimization of flash extraction, separation of ginsenosides, identification by HPLC-FT-ICR-MS and determination of rare ginsenosides in mountain cultivated ginseng

Contact Info

Product

Resources

About