The ratio of injection-production control area is an important aspect in evaluating the development effect and calculating oilfield development index. Conventional approaches to determine the ratio of injection-production control area neglect the heterogeneity of the reservoir and require long time simulating and a lot of complex iterations. This paper establishes a prediction formula to quickly determine the ratio of injection-production control area in triangle well pattern. A total of 410 sets of streamline models are built to acquire the database. Permeability, oil saturation, injection-production pressure drop and injector-producer spacing are selected as independent variables to establish the prediction formula by multivariate parametric regression. Based on error analysis and application, the accuracy of this prediction formula is approved. Results indicate that the prediction formula has a correlation coefficient R 2 of 0.96, representing a satisfactory performance. Normality and homoscedasticity tests and standardized residual diagnostics demonstrate the statistical significance of the results. The application of this prediction formula shows an excellent match between the predicted and actual injection-production area, which further confirms the accuracy of this prediction formula. The established prediction formula can effectively and accurately decide the ratio of injection-production control area for waterflooding reservoir.