For the first time, at the level of a popular scientific experimental publication, a theoretical substantiation of the need to introduce preventive and self-restorative methods in dentistry was carried out, thanks to the use of compositions with nano-silica, nano-aluminum oxide and micro-sized mineral plant fillers. Methods for creating tooth powders and epoxy polymer fillings are proposed -from publicly available components, for use by non-specialists in places unsuitable for traditional prevention. All these assumptions and hypotheses were confirmed in the obtained results of observations in the wellbeing of patients by visual information (photo, x-ray image) of the treated groups of affected teeth. The experimental part was based on the results of preclinical studies and was carried out on volunteers, with the involvement of consultants from dental clinics. The findings confirm the possibility of effective prevention and self-healing of dental systems through non-operative exposure to special complexes of dental powders, pastes and rinsing systems (subject to the correct mode of dental use).